Knowledge Management System Of Institute of High Energy
Pathophysiologic mechanisms of biomedical nanomaterials | |
Wang LM(王黎明)![]() | |
2016 | |
发表期刊 | TOXICOLOGY AND APPLIED PHARMACOLOGY (IF:3.791[JCR-2016],4.006[5-Year]) |
ISSN | 0041-008X |
EISSN | 1096-0333 |
卷号 | 299页码:30-40 |
文章类型 | Article |
摘要 | Nanomaterials (NMs) have been widespread used in biomedical fields, daily consuming, and even food industry. It is crucial to understand the safety and biomedical efficacy of NMs. In this review, we summarized the recent progress about the physiological and pathological effects of NMs from several levels: protein-nano interface, NM-subcellular structures, and cell-cell interaction. We focused on the detailed information of nano-bio interaction, especially about protein adsorption, intracellular trafficking, biological barriers, and signaling pathways as well as the associated mechanism mediated by nanomaterials. We also introduced related analytical methods that are meaningful and helpful for biomedical effect studies in the future. We believe that knowledge about pathophysiologic effects of NMs is not only significant for rational design of medical NMs but also helps predict their safety and further improve their applications in the future. (C) 2016 Elsevier Inc All rights reserved. |
关键词 | Nanomaterials Pathophysiologic effects Nano-bio interaction Safety Biomedical effects |
DOI | 10.1016/j.taap.2016.01.022 |
收录类别 | SCI ; ADS |
语种 | 英语 |
WOS记录号 | WOS:000374435900005 |
ADS Bibcode | 2016ToxAP.299...30W |
ADS URL | https://ui.adsabs.harvard.edu/abs/2016ToxAP.299...30W |
ADS引文 | https://ui.adsabs.harvard.edu/abs/2016ToxAP.299...30W/citations |
引用统计 | 正在获取...
被引频次:3 [ADS]
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文献类型 | 期刊论文 |
条目标识符 | https://ir.ihep.ac.cn/handle/311005/248018 |
专题 | 中国科学院高能物理研究所 |
推荐引用方式 GB/T 7714 | Wang LM,Chen CY,Wang, LM,et al. Pathophysiologic mechanisms of biomedical nanomaterials[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY,2016,299:30-40. |
APA | 王黎明,陈春英,Wang, LM,&Chen, CY.(2016).Pathophysiologic mechanisms of biomedical nanomaterials.TOXICOLOGY AND APPLIED PHARMACOLOGY,299,30-40. |
MLA | 王黎明,et al."Pathophysiologic mechanisms of biomedical nanomaterials".TOXICOLOGY AND APPLIED PHARMACOLOGY 299(2016):30-40. |
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