IHEP OpenIR  > 核技术应用研究中心
Grey matter morphological anomalies in the caudate head in first-episode psychosis patients with delusions of reference
Tao, HJ; Wong, GHY; Zhang, HR; Zhou, Y; Xue, ZM; Shan, BC; Chen, EYH; Liu, ZN; Dan BC(单保慈)
2015
发表期刊PSYCHIATRY RESEARCH-NEUROIMAGING
卷号233期号:1页码:57-63
文章类型Article
摘要Delusions of reference (DOR) are theoretically linked with aberrant salience and associative learning. Previous studies have shown that the caudate nucleus plays a critical role in the cognitive circuits of coding prediction errors and associative learning. The current study aimed at testing the hypothesis that abnormalities in the caudate nucleus may be involved in the neuroanatomical substrate of DOR. Structural magnetic resonance imaging of the brain was performed in 44 first-episode psychosis patients (with diagnoses of schizophrenia or schizophreniform disorder) and 25 healthy controls. Patients were divided into three groups according to symptoms: patients with DOR as prominent positive symptom; patients with prominent positive symptoms other than DOR; and patients with minimal positive symptoms. All groups were age-, gender-, and education-matched, and patient groups were matched for diagnosis, duration of illness, and antipsychotic treatment. Voxel-based morphometric analysis was performed to identify group differences in grey matter density. Relationships were explored between grey matter density and DOR. Patients with DOR were found to have reduced grey matter density in the caudate compared with patients without DOR and healthy controls. Grey matter density values of the left and right caudate head were negatively correlated with DOR severity. Decreased grey matter density in the caudate nucleus may underlie DOR in early psychosis. (C) 2015 Elsevier Ireland Ltd. All rights reserved
关键词Grey matter morphology Voxel-based morphometry Caudate Delusions
学科领域Neurosciences & Neurology; Psychiatry
DOI10.1016/j.pscychresns.2015.04.011
收录类别SCI
WOS类目Clinical Neurology ; Neuroimaging ; Psychiatry
WOS记录号WOS:000355671600008
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/228454
专题核技术应用研究中心
推荐引用方式
GB/T 7714
Tao, HJ,Wong, GHY,Zhang, HR,et al. Grey matter morphological anomalies in the caudate head in first-episode psychosis patients with delusions of reference[J]. PSYCHIATRY RESEARCH-NEUROIMAGING,2015,233(1):57-63.
APA Tao, HJ.,Wong, GHY.,Zhang, HR.,Zhou, Y.,Xue, ZM.,...&单保慈.(2015).Grey matter morphological anomalies in the caudate head in first-episode psychosis patients with delusions of reference.PSYCHIATRY RESEARCH-NEUROIMAGING,233(1),57-63.
MLA Tao, HJ,et al."Grey matter morphological anomalies in the caudate head in first-episode psychosis patients with delusions of reference".PSYCHIATRY RESEARCH-NEUROIMAGING 233.1(2015):57-63.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
391.pdf(2511KB)期刊论文作者接受稿限制开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Tao, HJ]的文章
[Wong, GHY]的文章
[Zhang, HR]的文章
百度学术
百度学术中相似的文章
[Tao, HJ]的文章
[Wong, GHY]的文章
[Zhang, HR]的文章
必应学术
必应学术中相似的文章
[Tao, HJ]的文章
[Wong, GHY]的文章
[Zhang, HR]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。