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中国科学院高能物理研究所机构知识库
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博士学位论文—不同小肽分子修饰的金纳米团簇的生物效应研究
学位论文
, 北京: 中国科学院大学, 2021
Authors:
何哲圣
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Submit date:2022/01/07
博士学位论文-帕金森病细胞模型中铁元素神经毒性的研究
学位论文
: 中国科学院高能物理研究所, 2019
Authors:
黄辉
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Submit date:2021/03/02
Exposure to Alumina Nanoparticles in Female Mice During Pregnancy Induces Neurodevelopmental Toxicity in the Offspring
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 253
Authors:
Zhang, QL
;
Ding, Y
;
He, KH
;
Li, H
;
Gao, FP
;
Moehling, TJ
;
Wu, XH
;
Duncan, J
;
Niu, Q
;
Gao FP(高福平)
Adobe PDF(1679Kb)
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WOS cited times:[0]
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Submit date:2019/09/24
alumina nanoparticles
developmental neurotoxicity
neurodevelopmental toxicity
oxidative stress
neurotransmitter
Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 4, 页码: 1192-1202
Authors:
Li, HH
;
Yang, K
;
Wang WJ(王文佳)
;
Dong YH(董宇辉)
;
Wang, WJ
;
Niu, YB
;
Li, J
;
Dong, YH
;
Liu, YF
;
Wang, CC
;
Wang, L
;
Liang, HH
Adobe PDF(1914Kb)
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WOS cited times:[0]
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Submit date:2019/09/24
conformational change
molecular chaperone
protein structure
small-angle X-ray scattering (SAXS)
X-ray crystallography
In Situ Monitoring the Aggregation Dynamics of Amyloid- Protein A´2 in Physiological Media via a Raman-Based Frequency Shift Method
期刊论文
ACS APPLIED BIO MATERIALS, 2018, 期号: 3, 页码: 814-824
Authors:
Zhu WF(朱文峰)
;
Xie D(谢丹)
;
Cheng LX(程林秀)
;
Li M(李敏)
;
Zhao YL(赵宇亮)
;
Zhu, Wenfeng, Wang, Yibing, Xie, Dan, Cheng, Linxiu, Wang, Ping, Zeng, Qingdao, Li, Min
;
Zhao, Yuliang
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Submit date:2019/10/10
Structure-function analyses reveal the molecular architecture and neutralization mechanism of a bacterial HEPN-MNT toxin-antitoxin system
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 18, 页码: 6812-6823
Authors:
Jia, XY
;
Yao, JY
;
Gao ZQ(高增强)
;
Dong YH(董宇辉)
;
Zhang H(张衡)
;
Gao, ZQ
;
Liu, GF
;
Dong, YH
;
Wang, XX
;
Zhang, H
Adobe PDF(1768Kb)
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WOS cited times:[0]
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Submit date:2019/09/24
toxin
crystal structure
small-angle X-ray scattering (SAXS)
RNA binding protein
RNA-protein interaction
RNA ribonuclease
toxin-antitoxin system
Iron-induced generation of mitochondrial ROS depends on AMPK activity
期刊论文
BIOMETALS, 2017, 卷号: 30, 期号: 4, 页码: 623-628
Authors:
Huang H(黄辉)
;
Chen J(陈俊)
;
Lu HR(卢会茹)
;
Zhou MX(周梦雪)
;
Chai ZF(柴之芳)
;
Hu Y(胡毅)
;
Huang, H
;
Chen, J
;
Lu, HR
;
Zhou, MX
;
Chai, ZF
;
Hu, Y
Adobe PDF(2868Kb)
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WOS cited times:[0]
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Submit date:2019/08/27
Fe(II)
AMPK
Neurotoxicity
Mitochondria
ROS
Iron modulates the activity of monoamine oxidase B in SH-SY5Y cells
期刊论文
BIOMETALS, 2017, 卷号: 30, 期号: 4, 页码: 599-607
Authors:
Lu HR(卢会茹)
;
Chen J(陈俊)
;
Huang H(黄辉)
;
Zhou MX(周梦雪)
;
Chai ZF(柴之芳)
;
Hu Y(胡毅)
;
Lu, HR
;
Chen, J
;
Huang, H
;
Zhou, MX
;
Zhu, Q
;
Yao, SQ
;
Chai, ZF
;
Hu, Y
Adobe PDF(3611Kb)
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Submit date:2019/08/27
Iron
MAO-B
Fluorescence probe
Long-term acupuncture treatment has a multi-targeting regulation on multiple brain regions in rats with Alzheimer's disease: a positron emission tomography study
期刊论文
NEURAL REGENERATION RESEARCH中国神经再生研究, 2017, 卷号: 12, 期号: 7, 页码: 1159-1165
Authors:
Lu, YJ
;
Cai, XW
;
Zhang, GF
;
Huang, Y
;
Tang, CZ
;
Shan, BC
;
Cui, SY
;
Chen, JQ
;
Qu, SS
;
Zhong, Z
;
Lai, XS
;
Steiner, GZ
;
Dan BC(单保慈)
Adobe PDF(1483Kb)
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WOS cited times:[0]
CSCD cited times:[1]
  |  
Submit date:2019/08/27
nerve regeneration
neurodegeneration
acupuncture
Zusanli (ST36)
Alzheimer's disease
long-term treatment
positron emission tomography
rat
mechanism
targeting effect
compensation
multi-target regulation
neural regeneration
Two mTOR inhibitors, rapamycin and Torin 1, differentially regulate iron-induced generation of mitochondrial ROS
期刊论文
BIOMETALS, 2017, 卷号: 30, 期号: 6, 页码: 975-980
Authors:
Huang H(黄辉)
;
Chen J(陈俊)
;
Lu HR(卢会茹)
;
Zhou MX(周梦雪)
;
Chai ZF(柴之芳)
;
Hu Y(胡毅)
;
Hui Huang
;
Jun Chen
;
Huiru Lu
;
Mengxue Zhou
;
Zhifang Chai
;
Yi Hu
Adobe PDF(744Kb)
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Submit date:2019/08/27
mTOR
Rapamycin
Torin 1
ROS