Biomimetic construction of protein-conjugated gold clusters for detecting Hg2+ | |
He, J![]() ![]() ![]() ![]() ![]() ![]() | |
2017 | |
Source Publication | COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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ISSN | 0927-7757 |
EISSN | 1873-4359 |
Volume | 518Pages:80-84 |
Subtype | Article |
Abstract | Mercury ion (Hg2+) pollution has deleterious effects on the environment and human health. Herein, through one-step biomimetic mineralization of metal salt with a natural protein, we develop an optical sensor system for Hg2+ detection with high selectivity and sensitivity. Glucose oxidase (GOD) serves as both a template and reducing agent to achieve the in situ biomineralization of Au (III), producing stable fluorescent GOD-conjugated gold clusters (GOD-AuCs) with a high yield. The probe above with a uniform core size of around 2.5 nm, has an obvious maximum fluorescence emission peak at 686 nm. GOD-AuCs exhibit good selectivity to Hg2+, in comparison to other metal ions including K+, Na+, Ca2+, Mg2+, Zn2+ and Cu2+. The reason might be that the existence of a small amount of Au+ (21%) on the surface of the cluster, permits strong metallophilic interaction between GOD-AuCs and Hg2+. It results in the instantaneous and remarkable fluorescence quench. Moreover, the intensity of fluorescence quench is found to be linearly depended on the concentration of Hg2+, with a detection limit of 7.5 mu M. These favorable findings promise GOD-AuCs have a good potential in monitoring environmental Hg2+. (C) 2017 Elsevier B.V. All rights reserved. |
Keyword | Metal cluster Biomineralization Fluorescence probe Hg2+ |
DOI | 10.1016/j.colsurfa.2017.01.018 |
WOS Keyword | BIOMEDICAL APPLICATIONS ; METAL NANOCLUSTERS ; AU NANOCLUSTERS ; CANCER |
Indexed By | SCI ; EI ; SCOPUS |
Language | 英语 |
WOS Research Area | Chemistry |
WOS Subject | Chemistry, Physical |
WOS ID | WOS:000395842900010 |
EI Accession Number | 20170303257781 |
EI Keywords | Biomimetics - Biomineralization - Fluorescence - Glucose oxidase - Glucose sensors - Gold - Metal ions - Probes |
EI Classification Number | 461.9 Biology - 462.1 Biomedical Equipment, General - 531.1 Metallurgy - 547.1 Precious Metals - 741.1 Light/Optics |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ihep.ac.cn/handle/311005/285178 |
Collection | 多学科研究中心 加速器中心 |
Affiliation | 中国科学院高能物理研究所 |
First Author Affilication | Institute of High Energy |
Recommended Citation GB/T 7714 | He, J,Liu, MQ,Gao FP,et al. Biomimetic construction of protein-conjugated gold clusters for detecting Hg2+[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2017,518:80-84. |
APA | He, J.,Liu, MQ.,高福平.,高靓.,高学云.,...&Han, R.(2017).Biomimetic construction of protein-conjugated gold clusters for detecting Hg2+.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,518,80-84. |
MLA | He, J,et al."Biomimetic construction of protein-conjugated gold clusters for detecting Hg2+".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 518(2017):80-84. |
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