| Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations | |
Wang, Y ; Jin, S; Li, J; Zhou, J; Zhang, LJ; Wang, JQ; Zhang, S; Wei, XJ; Jiang, Z; Huang, YY; Cui, PX; Zhao, HF; Chu, WS; Zhao HF(赵海峰); Chu SQ(储胜启)
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| 2017 | |
| Source Publication | RADIATION PHYSICS AND CHEMISTRY
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| ISSN | 0969-806X |
| Volume | 137Pages:88-92 |
| Subtype | Article; Proceedings Paper |
| Abstract | Copper/zinc superoxide dismutase (CuZnSOD) is an important enzyme that plays a crucial role in protecting oxygen-metabolizing cells against harmful effects of superoxide free-radicals. In this work, the three-dimensional local structure around the copper-binding site in pH 7.0 buffer solution was determined using X-ray absorption near-edge spectroscopy (XANES) combined with ab initio calculations in the framework of the multiple-scattering theory performed by MXAN. Extremely accurate bond distances and bond angle information between ligands were returned. The result confirmed that the copper ion binds four conserved His residues and a water molecule in CuZnSOD and prefers a five-coordinated in a distorted square pyramidal geometry. (C) 2016 Elsevier Ltd. All rights reserved. |
| Conference Title | 13th International Symposium on Radiation Physics (ISRP) |
| Conference Place | Univ Sci & Technol China, Beijing, PEOPLES R CHINA |
| Conference Date | SEP 07-11, 2015 |
| Keyword | Copper/zinc superoxide dismutase BioXAS Metalloprotein MXAN |
| DOI | 10.1016/j.radphyschem.2016.03.003 |
| WOS Keyword | X-RAY-ABSORPTION ; AMYOTROPHIC-LATERAL-SCLEROSIS ; IRON-MOLYBDENUM COFACTOR ; NEAR-EDGE STRUCTURE ; K-EDGE ; SPECTRA ; SPECTROSCOPY ; NITROGENASE ; IFEFFIT |
| Indexed By | SCI ; EI ; CPCI ; SCOPUS ; ADS |
| Language | 英语 |
| WOS Research Area | Chemistry ; Nuclear Science & Technology ; Physics |
| WOS Subject | Chemistry, Physical ; Nuclear Science & Technology ; Physics, Atomic, Molecular & Chemical |
| WOS ID | WOS:000404201800018 |
| EI Accession Number | 20161102083613 |
| EI Keywords | Calculations - Enzymes - Free radicals - Metal ions - Molecules - X ray absorption |
| EI Classification Number | 531.1 Metallurgy - 711 Electromagnetic Waves - 921 Mathematics - 931.3 Atomic and Molecular Physics |
| ADS Bibcode | 2017RaPC..137...88W |
| ADS URL | https://ui.adsabs.harvard.edu/abs/2017RaPC..137...88W |
| ADS CITATIONS | https://ui.adsabs.harvard.edu/abs/2017RaPC..137...88W/citations |
| Citation statistics |
Cited Times:0 [ADS]
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| Document Type | 期刊论文 |
| Identifier | http://ir.ihep.ac.cn/handle/311005/284924 |
| Collection | 多学科研究中心 粒子天体物理中心 |
| Affiliation | 中国科学院高能物理研究所 |
| First Author Affilication | Institute of High Energy |
| Recommended Citation GB/T 7714 | Wang, Y,Jin, S,Li, J,et al. Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations[J]. RADIATION PHYSICS AND CHEMISTRY,2017,137:88-92. |
| APA | Wang, Y.,Jin, S.,Li, J.,Zhou, J.,Zhang, LJ.,...&储胜启.(2017).Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations.RADIATION PHYSICS AND CHEMISTRY,137,88-92. |
| MLA | Wang, Y,et al."Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations".RADIATION PHYSICS AND CHEMISTRY 137(2017):88-92. |
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