Elemental Bio-imaging of Biological Samples by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry
Zhang XY(张新颖); Zheng LN(郑令娜); Wang HL(王海龙); Shi JW(史俊稳); Feng WY(丰伟悦); Wang M(王萌); Zhang, XY; Zheng, LN; Wang, HL; Shi, JW; Feng, WY; Li, L; Wang, M
刊名CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
2016
卷号44期号:11页码:1646-1651
关键词Inductively coupled plasma-mass spectrometry Laser ablation Elemental bio-imaging Single cell analysis Mouse brain sections Gold nanoparticles
DOI10.1016/S1872-2040(16)60969-6
其他题名基于激光剥蚀-电感耦合等离子体质谱技术的生物元素成像分析
通讯作者王萌
文章类型期刊论文
英文摘要Trace elements play very important roles in biological organism and are closely related to many diseases. New analytical methods are urgently needed for in situ determination of trace elements in biological tissues or single cells. A method based on laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) was developed here for in situ analysis. Line ablation mode was chosen and the output energy of the laser was optimized at a low fluence of less than 1 J cm(-2). Two kinds of elemental image of both a coronal section from mouse brain and single cells exposed to gold nanoparticles were obtained by the developed method. Due to the unique characteristic, such as good spatial resolution, excellent detection limit, and reasonable running cost, LA-ICP-MS will be applied widely and become a useful tool in biomedical research in the future.
类目[WOS]Chemistry, Analytical
关键词[WOS]LA-ICP-MS ; ALZHEIMERS-DISEASE ; QUANTITATIVE-ANALYSIS ; ZN ; CELL ; CU ; CO
语种中文
WOS记录号WOS:000389520000002
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/260490
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_加速器中心
中国科学院高能物理研究所_多学科研究中心
作者单位中国科学院高能物理研究所
推荐引用方式
GB/T 7714
Zhang XY,Zheng LN,Wang HL,et al. Elemental Bio-imaging of Biological Samples by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2016,44(11):1646-1651.
APA 张新颖.,郑令娜.,王海龙.,史俊稳.,丰伟悦.,...&Wang, M.(2016).Elemental Bio-imaging of Biological Samples by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,44(11),1646-1651.
MLA 张新颖,et al."Elemental Bio-imaging of Biological Samples by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 44.11(2016):1646-1651.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
20160906.pdf(1594KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[张新颖]的文章
[郑令娜]的文章
[王海龙]的文章
百度学术
百度学术中相似的文章
[张新颖]的文章
[郑令娜]的文章
[王海龙]的文章
必应学术
必应学术中相似的文章
[张新颖]的文章
[郑令娜]的文章
[王海龙]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 20160906.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。