IHEP OpenIR  > 多学科研究中心
Structural analysis of Pseudomonas aeruginosa H3-T6SS immunity proteins
Yang, XY; Li, ZQ; She Z(佘准); Geng Z(耿直); Xu JH(徐建华); Gao ZQ(高增强); Dong YH(董宇辉); She, Z; Geng, Z; Xu, JH; Gao, ZQ; Dong, YH
2016
发表期刊FEBS LETTERS
卷号590期号:16页码:2787-2796
通讯作者董宇辉
文章类型期刊论文
摘要The Pseudomonas aeruginosa PldB protein is a transkingdom effector secreted by the Type VI Secretion System (T6SS). PA5088, PA5087, and PA5086 are three immunity proteins that can suppress the virulence of PldB. We report the crystal structures of PA5088 and PA5087 at 2.0 and 2.1 angstrom resolution, respectively. PA5088 and PA5087 both consist of several Sel1-like Repeats (SLRs) and form super-ring folds. Our structural analysis of these proteins revealed key differences among PA5088, PA5087, and their homologs. Our docking experiments have shed light on the putative interaction mechanism of their function as phospholipase D inhibitors.
关键词immunity protein molecular docking Sel1-like repeats super-ring type VI secretion system
DOI10.1002/1873-3468.12291
关键词[WOS]SELF-PROTECTION MECHANISM ; CRYSTAL-STRUCTURE ; PHOSPHOLIPASE-D ; SECRETION SYSTEM ; EFFECTOR TSE1 ; INSIGHTS ; COMPLEX ; SERVER ; MODEL ; REVEALS
语种英语
WOS类目Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
WOS记录号WOS:000383600300029
引用统计
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/260413
专题多学科研究中心
作者单位中国科学院高能物理研究所
推荐引用方式
GB/T 7714
Yang, XY,Li, ZQ,She Z,et al. Structural analysis of Pseudomonas aeruginosa H3-T6SS immunity proteins[J]. FEBS LETTERS,2016,590(16):2787-2796.
APA Yang, XY.,Li, ZQ.,佘准.,耿直.,徐建华.,...&Dong, YH.(2016).Structural analysis of Pseudomonas aeruginosa H3-T6SS immunity proteins.FEBS LETTERS,590(16),2787-2796.
MLA Yang, XY,et al."Structural analysis of Pseudomonas aeruginosa H3-T6SS immunity proteins".FEBS LETTERS 590.16(2016):2787-2796.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
20160672.pdf(1530KB)期刊论文作者接受稿限制开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Yang, XY]的文章
[Li, ZQ]的文章
[佘准]的文章
百度学术
百度学术中相似的文章
[Yang, XY]的文章
[Li, ZQ]的文章
[佘准]的文章
必应学术
必应学术中相似的文章
[Yang, XY]的文章
[Li, ZQ]的文章
[佘准]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。