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Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent
Li J(李娟); Cui RL(崔荣丽); Chang YN(常亚男); Guo XH(郭喜红); Gu WH(古伟宏); Huang H(黄换); Chen K(陈奎); Lin GM(林国明); Dong JQ(董金泉); Xing GM(邢更妹); Sun BY(孙宝云); Li, J; Cui, RL; Chang, YN; Guo, XH; Gu, WH; Huang, H; Chen, K; Lin, GM; Dong, JQ; Xing, GM; Sun, BY
2016
发表期刊RSC ADVANCES
卷号6期号:63页码:58028-58033
通讯作者邢更妹 ; 孙宝云
摘要Water-soluble GO-Gd@C-82 nanohybrids exhibit high relaxivities and could be explored as potential magnetic resonance imaging (MRI) contrast agents. To better understand the relaxation mechanism in the novel carbon nanohybrids, in the present paper, after layers of in-depth analysis and exploration, we propose that the structure and the physicochemical properties of the carbon nanohybrids contribute significantly to the enhanced relaxivity. Better electron transfer from Gd@C-82 to the GO nanosheet, appropriate electric conductivity and size of the GO used, an increased number of H proton exchange sites and an adequate concentration of Gd3+ should result in optimal equilibrium for high relaxivity of the GO-Gd@C-82. These results are important for constructing and optimizing novel nanoscale architectures with higher relaxivity.
文章类型期刊论文
DOI10.1039/c6ra06733f
关键词[WOS]WATER-SOLUBLE GADOFULLERENES ; METALLOFULLERENES ; RELAXATION
语种英语
WOS类目Chemistry, Multidisciplinary
WOS记录号WOS:000378725800031
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/260293
专题多学科研究中心
作者单位中国科学院高能物理研究所
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GB/T 7714
Li J,Cui RL,Chang YN,et al. Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent[J]. RSC ADVANCES,2016,6(63):58028-58033.
APA 李娟.,崔荣丽.,常亚男.,郭喜红.,古伟宏.,...&Sun, BY.(2016).Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent.RSC ADVANCES,6(63),58028-58033.
MLA 李娟,et al."Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent".RSC ADVANCES 6.63(2016):58028-58033.
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