Viewing the Interaction Between Double Strand Deoxyribonucleic Acid and Graphene Oxide via Atomic Force Microscopy
Liu R(刘茹); Wei ZQ(魏钟晴); Li M(李敏); Zhao YL(赵宇亮); Liu, R; Wei, Z; Hu, Z; Li, M; Zhao, Y
刊名JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
2016
卷号16期号:4页码:4120-4125
关键词Graphene Oxide dsDNA Atomic Force Microscopy dsDNA-GO Interaction
DOI10.1166/jnn.2016.11903
通讯作者李敏
文章类型期刊论文
英文摘要The interaction between DNA and graphene-oxide (GO) is fundamental and of significance to a number of biomedical applications. It is fairly clear that pi-pi stacking effect accounts for the strong interaction between ssDNA and GO, while little is known on the mechanics of the relative weak interaction between dsDNA and GO. Here we employ AFM to investigate the coupling behavior of dsDNA-GO duplex and reveal preference adsorption of DNAon GO. The results show that dsDNA tends to aggregate on GO surface. Additionally, it is observed that GO also tend to stack into multi layer structure in the presence of dsDNA, indicating dsDNA can simultaneously interact with two sides of the GO sheet, Such a structure is, however, unstable and can easily collapse by rinsing or heating.
类目[WOS]Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
关键词[WOS]CARBON NANOTUBES ; AQUEOUS-SOLUTION ; DRUG-DELIVERY ; NANO-GRAPHENE ; DNA ; FLUORESCENCE ; SENSORS
语种英语
WOS记录号WOS:000386122700178
引用统计
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/260268
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_多学科研究中心
作者单位中国科学院高能物理研究所
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GB/T 7714
Liu R,Wei ZQ,Li M,et al. Viewing the Interaction Between Double Strand Deoxyribonucleic Acid and Graphene Oxide via Atomic Force Microscopy[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2016,16(4):4120-4125.
APA 刘茹.,魏钟晴.,李敏.,赵宇亮.,Liu, R.,...&Zhao, Y.(2016).Viewing the Interaction Between Double Strand Deoxyribonucleic Acid and Graphene Oxide via Atomic Force Microscopy.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,16(4),4120-4125.
MLA 刘茹,et al."Viewing the Interaction Between Double Strand Deoxyribonucleic Acid and Graphene Oxide via Atomic Force Microscopy".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 16.4(2016):4120-4125.
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