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Peptide protected gold clusters: chemical synthesis and biomedical applications
Yuan Q(袁卿); Wang YL(王亚玲); Zhao LN(赵丽娜); Liu R(刘茹); Gao FP(高福平); Gao J(高靓); Gao XY(高学云); Yuan, Q; Wang, YL; Zhao, LN; Liu, R; Gao, FP; Gao, L; Gao, XY
Source PublicationNANOSCALE
AbstractBridging the gap between atoms and nanoparticles, noble metal clusters with atomic precision continue to attract considerable attention due to their important applications in catalysis, energy transformation, biosensing and biomedicine. Greatly different to common chemical synthesis, a one-step biomimetic synthesis of peptide-conjugated metal clusters has been developed to meet the demand of emerging bioapplications. Under mild conditions, multifunctional peptides containing metal capturing, reactive and targeting groups are rationally designed and elaborately synthesized to fabricate atomically precise peptide protected metal clusters. Among them, peptide-protected Au Cs (peptide-Au Cs) possess a great deal of exceptional advantages such as nanometer dimensions, high photostability, good biocompatibility, accurate chemical formula and specific protein targeting capacity. In this review article, we focus on the recent advances in potential theranostic fields by introducing the rising progress of peptide-Au Cs for biological imaging, biological analysis and therapeutic applications. The interactions between Au Cs and biological systems as well as potential mechanisms are also our concerned theme. We expect that the rapidly growing interest in Au Cs-based theranostic applications will attract broader concerns across various disciplines.
Indexed BySCI ; ADS
WOS IDWOS:000378244900001
ADS Bibcode2016Nanos...812095Y
ADS URLhttps://ui.adsabs.harvard.edu/abs/2016Nanos...812095Y
ADS CITATIONShttps://ui.adsabs.harvard.edu/abs/2016Nanos...812095Y/citations
Citation statistics
Cited Times:12 [ADS]
Document Type期刊论文
Recommended Citation
GB/T 7714
Yuan Q,Wang YL,Zhao LN,et al. Peptide protected gold clusters: chemical synthesis and biomedical applications[J]. NANOSCALE,2016,8(24):12095-12104.
APA 袁卿.,王亚玲.,赵丽娜.,刘茹.,高福平.,...&Gao, XY.(2016).Peptide protected gold clusters: chemical synthesis and biomedical applications.NANOSCALE,8(24),12095-12104.
MLA 袁卿,et al."Peptide protected gold clusters: chemical synthesis and biomedical applications".NANOSCALE 8.24(2016):12095-12104.
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