Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
Zhao F(赵峰); Zhao Y(赵颖); Chang XL(常雪灵); Chen CY(陈春英); Zhao YL(赵宇亮); Zhao, F; Zhao, Y; Liu, Y; Chang, XL; Chen, CY; Zhao, YL
刊名SMALL
2011
卷号7期号:10页码:1322-1337
学科分类Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1002/smll.201100001
通讯作者[Zhao, Feng ; Zhao, Ying ; Chang, Xueling ; Chen, Chunying ; Zhao, Yuliang] Chinese Acad Sci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Inst High Energy Phys, Beijing 100049, Peoples R China ; [Zhao, Ying ; Liu, Ying ; Chen, Chunying ; Zhao, Yuliang] Natl Ctr Nanosci & Technol China, Beijing 100190, Peoples R China
文章类型Review
英文摘要The interactions of nanoparticles with the soft surfaces of biological systems like cells play key roles in executing their biomedical functions and in toxicity. The discovery or design of new biomedical functions, or the prediction of the toxicological consequences of nanoparticles in vivo, first require knowledge of the interplay processes of the nanoparticles with the target cells. This article focusses on the cellular uptake, location and translocation, and any biological consequences, such as cytotoxicity, of the most widely studied and used nanoparticles, such as carbon-based nanoparticles, metallic nanoparticles, and quantum dots. The relevance of the size and shape, composition, charge, and surface chemistry of the nanoparticles in cells is considered. The intracellular uptake pathways of the nanoparticles and the cellular responses, with potential signaling pathways activated by nanoparticle interactions, are also discussed.
类目[WOS]Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
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语种英语
WOS记录号WOS:000291087900004
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被引频次:415[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/239278
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_加速器中心
中国科学院高能物理研究所_多学科研究中心
作者单位中国科学院高能物理研究所
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GB/T 7714
Zhao F,Zhao Y,Chang XL,et al. Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials[J]. SMALL,2011,7(10):1322-1337.
APA 赵峰.,赵颖.,常雪灵.,陈春英.,赵宇亮.,...&Zhao, YL.(2011).Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials.SMALL,7(10),1322-1337.
MLA 赵峰,et al."Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials".SMALL 7.10(2011):1322-1337.
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