Aichi Univ, Aichi 4700296, Japan
; Ochanomizu Univ, Dept Phys, Tokyo 1128610, Japan
; Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China
; Niigata Univ, Dept Phys, Niigata 9502128, Japan
We study the SUSY SO(10) GUT with the symmetric two-zero textures of the quark/lepton mass matrix which realize the Georgi-Jarlskog relations in down-type quark and charged lepton masses. We show that the important constraints on such a framework come from the bottom-tau unification and the observed value of sin 2 beta, one of the angles in the CKM unitarity triangle. We investigate the symmetric two-zero textures assumed at the GUT scale by solving the MSSM renormalization group equations with right-handed neutrino threshold effects. Our results indicate that the value of tan (beta) over tilde is large and the representation of the Higgs field which couples to the third generation of left- and right-handed neutrinos is restricted by the bottom-tau unification condition. The textures with a vanishing 1-2 (and 2-1) element for up-type quarks and a vanishing 1-3 (and 3-1) element for down-type quarks are favored by the observed value of sin 2 beta.