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Biodistribution of carbon single-wall carbon nanotubes in mice
Wang, HF; Wang, J; Deng, XY; Sun, HF; Shi, ZJ; Gu, ZN; Liu, YF; Zhao, YL; Zhao YL(赵宇亮)
2004
发表期刊JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷号4期号:8页码:1019-1024
通讯作者Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Beijing 100871, Peoples R China ; Peking Univ, Inst Inorgan Chem, Coll Chem & Mol Engn, Beijing 100871, Peoples R China ; Chinese Acad Sci, Inst High Energy Phys, Beijing 100039, Peoples R China
摘要Carbon nanotubes are promising for use in biomedical and pharmaceutical sciences. Therefore, it becomes imperative to know the basic biological properties of carbon nanotubes in vivo. We labeled the water-soluble hydroxylated carbon single-wall nanotubes with radioactive I-125 atoms, and then the tracer was used to study the distribution of hydroxylated carbon single-wall nanotubes in mice. They moved easily among the compartments and tissues of the body, behaving as small active molecules though their apparent mean molecular weight is tremendously large. This study, for the first time, affords a quantitative analysis of carbon nanotubes accumulated in animal tissues.
文章类型Article
关键词carbon single-wall nanotubes water-soluble (125)l-labeling distribution in vivo
学科领域Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1166/jnn.2004.146
研究领域[WOS]Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
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语种英语
WOS类目Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS记录号WOS:000225872000013
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文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/238904
专题多学科研究中心
作者单位中国科学院高能物理研究所
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Wang, HF,Wang, J,Deng, XY,et al. Biodistribution of carbon single-wall carbon nanotubes in mice[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2004,4(8):1019-1024.
APA Wang, HF.,Wang, J.,Deng, XY.,Sun, HF.,Shi, ZJ.,...&赵宇亮.(2004).Biodistribution of carbon single-wall carbon nanotubes in mice.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,4(8),1019-1024.
MLA Wang, HF,et al."Biodistribution of carbon single-wall carbon nanotubes in mice".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 4.8(2004):1019-1024.
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