IHEP OpenIR  > 多学科研究中心
Structure of orotate phosphoribosyltransferase from the caries pathogen Streptococcus mutans
Liu CP(刘超培); Xu R(许锐); Gao ZQ(高增强); Xu JH(徐建华); Hou HF(侯海峰); Li LQ(李丽琴); She Z(佘准); 刘鹏(多); Dong YH(董宇辉); Liu, CP; Xu, R; Gao, ZQ; Xu, JH; Hou, HF; Li, LQ; She, Z; Li, LF; Su, XD; Liu, P; Dong, YH
2010
发表期刊ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
卷号66期号:5页码:498-502
通讯作者[Liu, Chao-Pei ; Xu, Rui ; Gao, Zeng-Qiang ; Xu, Jian-Hua ; Hou, Hai-Feng ; Li, Li-Qin ; She, Zhun ; Liu, Peng ; Dong, Yu-Hui] Chinese Acad Sci, Inst High Energy Phys, Beijing Synchrotron Radiat Facil, Beijing 100049, Peoples R China ; [Liu, Chao-Pei ; Li, Li-Qin ; She, Zhun] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China ; [Li, Lan-Fen ; Su, Xiao-Dong] Peking Univ, Coll Life Sci, Natl Lab Prot Engn & Plant Genet Engn, Beijing 100871, Peoples R China
文章类型Article
摘要Orotate phosphoribosyltransferase (OPRTase) catalyzes the OMP-forming step in de novo pyrimidine-nucleotide biosynthesis. Here, the crystal structure of OPRTase from the caries pathogen Streptococcus mutans is reported at 2.4 angstrom resolution. S. mutans OPRTase forms a symmetric dimer and each monomer binds two sulfates at the active sites. The structural symmetry of the sulfate-binding sites and the missing loops in this structure are consistent with a symmetric catalysis mechanism.
学科领域Biochemistry & Molecular Biology; Biophysics; Crystallography
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics ; Crystallography ; Biochemistry & Molecular Biology ; Biophysics ; Crystallography
DOI10.1107/S1744309110009243
URL查看原文
语种英语
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics ; Crystallography ; Biochemistry & Molecular Biology ; Biophysics ; Crystallography
WOS类目Biochemical Research Methods ; Biochemistry & Molecular Biology ; Biophysics ; Crystallography
WOS记录号WOS:000277217700003
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/237726
专题多学科研究中心
理论物理室
作者单位中国科学院高能物理研究所
推荐引用方式
GB/T 7714
Liu CP,Xu R,Gao ZQ,et al. Structure of orotate phosphoribosyltransferase from the caries pathogen Streptococcus mutans[J]. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS,2010,66(5):498-502.
APA 刘超培.,许锐.,高增强.,徐建华.,侯海峰.,...&Dong, YH.(2010).Structure of orotate phosphoribosyltransferase from the caries pathogen Streptococcus mutans.ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS,66(5),498-502.
MLA 刘超培,et al."Structure of orotate phosphoribosyltransferase from the caries pathogen Streptococcus mutans".ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 66.5(2010):498-502.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
4363.pdf(898KB)期刊论文作者接受稿限制开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[刘超培]的文章
[许锐]的文章
[高增强]的文章
百度学术
百度学术中相似的文章
[刘超培]的文章
[许锐]的文章
[高增强]的文章
必应学术
必应学术中相似的文章
[刘超培]的文章
[许锐]的文章
[高增强]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。