Chinese Acad Sci, Inst High Energy Phys, Lab Nucl Analyt Tech, Beijing 100080, Peoples R China
In the present study a method using enriched stable isotope tracer and instrumental neutron activation analysis (INAA) was developed to study the dynamic distribution of rare earth elements (REEs) in a variety of organs and tissues of Wistar rats. Stable isotopes Sm-152 and Yb-168 were selected as tracers for the experiment. Intravenously injected Sm-152 and Yb-168 in chloride form could be quickly absorbed and distributed in almost all the organs and tissues of interest. including liver, skeleton, kidney, spleen, heart, lung, testicle, and blood serum. Liver and skeleton had high ability to take up Sm-152 and Yb-168 under the experimental conditions, whereas the contents of the elements in other organs were generally lower than 2% of the given dose during the whole experimental period. The difference in distribution of Sm-152 and Yb-168 in the body was also discussed.
Li FL,Wang YQ,Zhang ZY,et al. Distribution of samarium. and ytterbium in rats measured by enriched stable isotope tracer technique and INAA[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2002,251(3):437-441.
李福亮.,王玉琦.,张智勇.,孙景信.,肖海清.,...&Chai, ZF.(2002).Distribution of samarium. and ytterbium in rats measured by enriched stable isotope tracer technique and INAA.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,251(3),437-441.
李福亮,et al."Distribution of samarium. and ytterbium in rats measured by enriched stable isotope tracer technique and INAA".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 251.3(2002):437-441.