Study of rare earth encapsulated carbon nanomolecules for biomedical uses
Qu L(屈力); Cao WB(曹文彬); Xing GM(邢更妹); Zhang J(张俊); Yuan H(袁慧); Tang J(唐军); Cheng Y(程悦); Zhang B(张波); Zhao YL(赵宇亮); Qu, L; Cao, WB; Xing, GM; Zhang, J; Yuan, H; Tang, J; Cheng, Y; Zhang, B; Zhao, YL; Lei, H
刊名JOURNAL OF ALLOYS AND COMPOUNDS
2006
卷号408页码:400-404
关键词Gd-metallofullerenol Gd@C-82(OH)(22) stability MRI contrast agent in vivo
学科分类Chemistry; Materials Science; Metallurgy & Metallurgical Engineering
DOI10.1016/j.jallcom.2004.12.101
通讯作者Chinese Acad Sci, Inst High Energy Phys, Lab Bioenvironm Hlth Sci Nanoscale Mat, Beijing 100039, Peoples R China ; Chinese Acad Sci, Inst Phys & Math, State Key Lab Nucl Magnet Resonance & Atom & Mol, Wuhan 430071, Peoples R China
文章类型Article; Proceedings Paper
英文摘要Gd@C-82(OH)(40) has been proposed to be as a new generation of the magnetic resonance imaging (MRI) contrast agent, but water-soluble fullerenols Gd@C-82(OH)(n) with n > 36 can easily lead to open-caged structures of a high instability. This restricts the practical bio-uses of Gd-metallofullerenols with a large number of hydroxyl groups. To explore how the imaging efficiency varies with decreasing hydroxyl number in Gd@C-82(OH)(22) of a good stability in vivo, Gd@C-82(OH)(22) was prepared, characterized and its imaging efficiency in mice was studied. This work aims at searching a chemical form of water-soluble Gd-metallofullerenols that satisfy both requirements of the good stability and high imaging efficiency in vivo. The results indicate that the proton relaxivity of Gd@C-82(OH)(22) is lower than that of Gd@C-82(OH)(40), but still higher than the commercial Gd-DTPA MRI contrast agent. (c) 2005 Elsevier B.V. All rights reserved.
类目[WOS]Chemistry, Physical ; Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
研究领域[WOS]Chemistry ; Materials Science ; Metallurgy & Metallurgical Engineering
原文出处查看原文
语种英语
WOS记录号WOS:000235445300097
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/237329
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_实验物理中心
中国科学院高能物理研究所_加速器中心
中国科学院高能物理研究所_多学科研究中心
作者单位中国科学院高能物理研究所
推荐引用方式
GB/T 7714
Qu L,Cao WB,Xing GM,et al. Study of rare earth encapsulated carbon nanomolecules for biomedical uses[J]. JOURNAL OF ALLOYS AND COMPOUNDS,2006,408:400-404.
APA 屈力.,曹文彬.,邢更妹.,张俊.,袁慧.,...&Lei, H.(2006).Study of rare earth encapsulated carbon nanomolecules for biomedical uses.JOURNAL OF ALLOYS AND COMPOUNDS,408,400-404.
MLA 屈力,et al."Study of rare earth encapsulated carbon nanomolecules for biomedical uses".JOURNAL OF ALLOYS AND COMPOUNDS 408(2006):400-404.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
3754.pdf(211KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[屈力]的文章
[曹文彬]的文章
[邢更妹]的文章
百度学术
百度学术中相似的文章
[屈力]的文章
[曹文彬]的文章
[邢更妹]的文章
必应学术
必应学术中相似的文章
[屈力]的文章
[曹文彬]的文章
[邢更妹]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 3754.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。