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A micro-tomography method based on X-ray diffraction enhanced imaging for the visualization of micro-organs and soft tissues
Gao, X; Luo, SQ; Yin, HX; Liu, B; Xu, ML; Yuan, QX; Gao, XL; Zhu, PP; Yuan QX(袁清习); Zhu PP(朱佩平)
2006
发表期刊COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
卷号30期号:6-7页码:339-347
通讯作者Capital Univ Med Sci, Med Image Lab, Coll Biomed Engn, Beijing 100069, Peoples R China ; Capital Univ Med Sci, Dept Anat, Beijing 100069, Peoples R China ; Chinese Acad Sci, Natl Lab Pattern Recognit, Beijing, Peoples R China ; Chinese Acad Sci, Inst High Energy Phys, Beijing, Peoples R China ; Beijing Informat Technol Inst, Beijing, Peoples R China
摘要Diffraction enhanced imaging (DEI) is one of the phase contrast imaging methods using the monochromatic X-ray from synchrotron, which provides information on the out-of-plane angular deviation of X-ray. DO allows the investigation of micro-structures inside weakly absorbing samples at high spatial resolution without serious radiation exposure. Tomographic techniques can be applied readily to phase contrast images. The combination of DEI and tomography allows for a reconstruction of refractive index gradient distribution inside weakly absorbing samples with micrometer resolution, particularly suited for the 3D observation of micro-organisms and tissues. The existing phase contrast tomography methods based on DEI use phase contrast images as projections, such images contain not only the phase information, but also the absorption information. A novel method (DEI in the tomography mode) was developed to greatly increase the proportion of refraction information in phase contrast images by computing the difference between the two sets of images acquired at different angles of the rocking curve to adopt the projections with a complete set (2 pi) for reconstruction. The reconstructed images of cochlea of a guinea pig showed the spatial structures and the micro-features inside the samples. The new method reveals higher spatial resolution compared to the conventional phase contrast tomography methods and is more suitable to the investigation of micro- structures of micro-organisms and tissue materials. (c) 2006 Elsevier Ltd. All rights reserved.
文章类型Article; Proceedings Paper
关键词micro-tomography diffraction enhanced imaging ohase contrast imaging high resolution cochlea of guinea pig liver tissues
学科领域Radiology, Nuclear Medicine & Medical Imaging
DOI10.1016/j.compmedimag.2006.09.003
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
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语种英语
WOS类目Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000242759900003
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被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/237054
专题多学科研究中心
作者单位中国科学院高能物理研究所
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GB/T 7714
Gao, X,Luo, SQ,Yin, HX,et al. A micro-tomography method based on X-ray diffraction enhanced imaging for the visualization of micro-organs and soft tissues[J]. COMPUTERIZED MEDICAL IMAGING AND GRAPHICS,2006,30(6-7):339-347.
APA Gao, X.,Luo, SQ.,Yin, HX.,Liu, B.,Xu, ML.,...&朱佩平.(2006).A micro-tomography method based on X-ray diffraction enhanced imaging for the visualization of micro-organs and soft tissues.COMPUTERIZED MEDICAL IMAGING AND GRAPHICS,30(6-7),339-347.
MLA Gao, X,et al."A micro-tomography method based on X-ray diffraction enhanced imaging for the visualization of micro-organs and soft tissues".COMPUTERIZED MEDICAL IMAGING AND GRAPHICS 30.6-7(2006):339-347.
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