Chinese Acad Sci, Inst High Energy Phys, Beijing, Peoples R China
; Chinese Acad Sci, Lab Nucl Anal Techniques, Beijing, Peoples R China
Article; Proceedings Paper
Chromium speciation was investigated in the liver cytosol, serum and urine of normal and diabetic rats after a single intravenous injection of enriched stable isotope Cr-50 tracer solution. Sephadex G-25 gel chromatography combined with instrumental neutron activation analysis was used to isolate and characterize protein-bound chromium in the above materials. The results indicate that Cr is mainly combined with a high-molecular-weight protein either in liver cytosol or serum. A low-molecular-weight, Cr-containing compound (LMWCr) was found in all the observed liver, serum and urine samples of both normal and diabetic rats. Chromium is excreted chiefly as LMWCr in urine.
Feng WY,Qian QF,Ding WJ,et al. Study of chromium speciation in normal and diabetic rats by activable enriched stable isotope technique[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2000,244(2):321-325.
丰伟悦.,钱琴芳.,丁万见.,柴之芳.,Feng, WY.,...&Chai, ZF.(2000).Study of chromium speciation in normal and diabetic rats by activable enriched stable isotope technique.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,244(2),321-325.
丰伟悦,et al."Study of chromium speciation in normal and diabetic rats by activable enriched stable isotope technique".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 244.2(2000):321-325.