Phase-contrast imaging with synchrotron hard X-ray of micro lesions of the cartilage of the femoral head in rabbits
Sun, W; Zhang, Y; Gao, FQ; Li, ZR; Li, G; Pan, L; Li G(黎刚)
2015
卷号8期号:11页码:20086-20091
关键词Phase-contrast synchrotron femoral head cartilage
学科分类Research & Experimental Medicine
文章类型Article
英文摘要Background: To observe micro lesions on the cartilage of the rabbit femoral head using phase-contrast imaging with synchrotron hard X-ray and to prove that this method can be useful in the study of the degeneration of cartilage. Methods: New Zealand white rabbits were used in a micro lesion model of rabbit femoral head cartilage. Bilateral femoral heads were excised from rabbits, and micro lesions were made on one side with a specially made knife with a blade 20 mu m in width. The other femur was left intact to serve as the control. Phase-contrast imaging with synchrotron hard X-ray and conventional X-ray imaging were used to observe the cartilage. Histological changes were investigated using modified Golden tri-color staining. Results: Phase-contrast imaging with synchrotron hard X-ray clearly showed the 20 mu m lesions on the cartilage on the heads of rabbit femurs. These lesions were not visible with conventional X-ray imaging. Histological observation confirmed the presence of the microscopic lesions. Conclusion: Phase-contrast imaging with synchrotron hard X-ray can detect microscopic lesions on cartilage that cannot be detected by conventional absorption-contrast X-ray. This provides an unequivocal, non-invasive alternative to histological examination in the diagnosis of joint disease. It should be considered a new tool in osteoarthritis and cartilage research.
类目[WOS]Medicine, Research & Experimental
收录类别SCI
WOS记录号WOS:000371013200032
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/229273
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
推荐引用方式
GB/T 7714
Sun, W,Zhang, Y,Gao, FQ,et al. Phase-contrast imaging with synchrotron hard X-ray of micro lesions of the cartilage of the femoral head in rabbits[J],2015,8(11):20086-20091.
APA Sun, W.,Zhang, Y.,Gao, FQ.,Li, ZR.,Li, G.,...&黎刚.(2015).Phase-contrast imaging with synchrotron hard X-ray of micro lesions of the cartilage of the femoral head in rabbits.,8(11),20086-20091.
MLA Sun, W,et al."Phase-contrast imaging with synchrotron hard X-ray of micro lesions of the cartilage of the femoral head in rabbits".8.11(2015):20086-20091.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
7232.pdf(932KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Sun, W]的文章
[Zhang, Y]的文章
[Gao, FQ]的文章
百度学术
百度学术中相似的文章
[Sun, W]的文章
[Zhang, Y]的文章
[Gao, FQ]的文章
必应学术
必应学术中相似的文章
[Sun, W]的文章
[Zhang, Y]的文章
[Gao, FQ]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 7232.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。