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Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi)
Li L(李琳); Gu XY(顾笑悦); Li DW(李道武); Huang XC(黄先超); Chai P(柴培); Feng BT(丰宝桐); Wang PL(王培林); Yuan MK(贠明凯); Zhang ZM(章志明); Yin PF(尹鹏飞); Wei L(魏龙); Li; L.; X. Y. Gu; D. W. Li; X. C. Huang; P. Chai; B. T. Feng; P. L. Wang; M. K. Yun; D. Dai; Z. M. Zhang; P. F. Yin; W. G. Xu and L. Wei
2015
发表期刊IEEE TRANSACTIONS ON NUCLEAR SCIENCE
卷号62期号:5页码:2048-2056
通讯作者李琳
摘要A new polygon positron emission mammography imaging system (PEMi) was developed in 2009 by the Institute of High Energy Physics, Chinese Academy of Sciences. PEMi is constructed in a polygon structure with lutetium yttrium orthosilicate crystal arrays mounted on a position-sensitive photomultiplier. The system consists of 64 blocks and each block is arranged in crystal arrays with a pixel size of 1.9 x 1.9 x 15 mm. The diameter of the detector ring is 166 mm, and the axial length is 128 mm. The transaxial field of view of PEMi is 110 mm. The goal of the initial study was to test PEMi's performance and the clinical imaging ability with a small group of selected subjects. The detectors have a measured intrinsic spatial resolution averaging 1.67 mm. The axial and tangential resolution remained under 2.5-mm full width at half maximum within the central 5-cm diameter of the field of view. The hot rods with a diameter of 1.7 mm can be clearly identified, and the structure of the region containing 1.35-mm diameter rods can also be observed. Using a 6-ns coincidence timing window and a 360 similar to 660-keV energy window, the peak sensitivity of the tomograph is 6.88%. The noise-equivalent count rate peak is 110 766 cps for a breast-like cylindrical phantom of 100 mm in diameter at an activity concentration of 0.03 MBq/cc. The recovery coefficients ranged from 0.21 to 0.85 for rods between 1 mm and 5 mm in the image-quality phantom. The reconstructed image resolution achieved an improvement compared with whole-body positron emission tomography (PET), which might reduce the lower threshold on detectable lesion size. Example patient images demonstrate that PEMi is clinically feasible. And more detailed structure information was obtained with PEMi than with the whole-body PET imaging.
文章类型Article
关键词Biomedical imaging breast cancer gamma-ray detectors positron emission mammography (PEM) positron emission tomography (PET)
学科领域Engineering; Nuclear Science & Technology
DOI10.1109/TNS.2015.2457957
收录类别SCI
WOS类目Engineering, Electrical & Electronic ; Nuclear Science & Technology
WOS记录号WOS:000363242200017
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被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/229009
专题核技术应用研究中心
中国科学院高能物理研究所_中国散裂中子源
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Li L,Gu XY,Li DW,et al. Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi)[J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE,2015,62(5):2048-2056.
APA 李琳.,顾笑悦.,李道武.,黄先超.,柴培.,...&W. G. Xu and L. Wei.(2015).Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi).IEEE TRANSACTIONS ON NUCLEAR SCIENCE,62(5),2048-2056.
MLA 李琳,et al."Performance Evaluation and Initial Clinical Test of the Positron Emission Mammography System (PEMi)".IEEE TRANSACTIONS ON NUCLEAR SCIENCE 62.5(2015):2048-2056.
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