Recent Advances in Upconversion Nanoparticles-Based Multifunctional Nanocomposites for Combined Cancer Therapy
Tian G(田甘); Zhang X(张潇); Gu ZJ(谷战军); Zhao YL(赵宇亮); Tian, G; Zhang, X; Gu, ZJ; Zhao, YL
刊名ADVANCED MATERIALS
2015
卷号27期号:47页码:7692-7712
学科分类Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1002/adma.201503280
通讯作者谷战军 ; 赵宇亮
文章类型Review
英文摘要Lanthanide-doped upconversion nanoparticles (UCNPs) have the ability to generate ultraviolet or visible emissions under continuous-wave near-infrared (NIR) excitation. Utilizing this special luminescence property, UCNPs are approved as a new generation of contrast agents in optical imaging with deep tissue-penetration ability and high signal-to-noise ratio. The integration of UCNPs with other functional moieties can endow them with highly enriched functionalities for imaging-guided cancer therapy, which makes composites based on UCNPs emerge as a new class of theranostic agents in biomedicine. Here, recent progress in combined cancer therapy using functional nanocomposites based on UCNPs is reviewed. Combined therapy referring to the co-delivery of two or more therapeutic agents or a combination of different treatments is becoming more popular in clinical treatment of cancer because it generates synergistic anti-cancer effects, reduces individual drug-related toxicity and suppresses multi-drug resistance through different mechanisms of action. Here, the recent advances of combined therapy contributed by UCNPs-based nanocomposites on two main branches are reviewed: i) photodynamic therapy and ii) chemotherapy, which are the two most widely adopted therapies of UCNPs-based composites. The future prospects and challenges in this emerging field will be also discussed.
类目[WOS]Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
收录类别SCI ; EI ; CA
WOS记录号WOS:000367837900001
引用统计
被引频次:50[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/228867
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_多学科研究中心
推荐引用方式
GB/T 7714
Tian G,Zhang X,Gu ZJ,et al. Recent Advances in Upconversion Nanoparticles-Based Multifunctional Nanocomposites for Combined Cancer Therapy[J]. ADVANCED MATERIALS,2015,27(47):7692-7712.
APA 田甘.,张潇.,谷战军.,赵宇亮.,Tian, G.,...&Zhao, YL.(2015).Recent Advances in Upconversion Nanoparticles-Based Multifunctional Nanocomposites for Combined Cancer Therapy.ADVANCED MATERIALS,27(47),7692-7712.
MLA 田甘,et al."Recent Advances in Upconversion Nanoparticles-Based Multifunctional Nanocomposites for Combined Cancer Therapy".ADVANCED MATERIALS 27.47(2015):7692-7712.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2003.pdf(7033KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[田甘]的文章
[张潇]的文章
[谷战军]的文章
百度学术
百度学术中相似的文章
[田甘]的文章
[张潇]的文章
[谷战军]的文章
必应学术
必应学术中相似的文章
[田甘]的文章
[张潇]的文章
[谷战军]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 2003.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。