Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents
Cui RL(崔荣丽); Li J(李娟); Huang H(黄换); Zhang MY(张铭倚); Guo XH(郭喜红); Li M(李敏); Dong JQ(董金泉); Sun BY(孙宝云); Xing GM(邢更妹); Cui, RL; Li, J; Huang, H; Zhang, MY; Guo, XH; Chang, YA; Li, M; Dong, JQ; Sun, BY; Xing, GM
刊名NANO RESEARCH
2015
卷号8期号:4页码:1259-1268
关键词graphene oxide metallofullerene magnetic resonance imaging (MRI) nanohybrids
学科分类Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1007/s12274-014-0613-x
通讯作者孙宝云 ; 邢更妹
文章类型Article
英文摘要Novel carbon nanohybrids based on unmodified metallofullerenes have been successfully fabricated for use as a new magnetic resonance imaging (MRI) contrast agent. The nanohybrids showed higher R (1) relaxivity and better brightening effect than Gd@C-82(OH) (X) , in T (1)-weighted MR images in vivo. This is a result of the proton relaxivity from the original gadofullerenes, which retained a perfect carbon cage structure and so might completely avoid the release of Gd3+ ions. A "secondary spin-electron transfer" relaxation mechanism was proposed to explain how the encaged Gd3+ ions of carbon nanohybrids interact with the surrounding water molecules. This approach opens new opportunities for developing highly efficient and low toxicity MRI contrast agents.
类目[WOS]Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
收录类别SCI ; CA
WOS记录号WOS:000353807500020
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被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/228294
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_多学科研究中心
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Cui RL,Li J,Huang H,et al. Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents[J]. NANO RESEARCH,2015,8(4):1259-1268.
APA 崔荣丽.,李娟.,黄换.,张铭倚.,郭喜红.,...&Xing, GM.(2015).Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents.NANO RESEARCH,8(4),1259-1268.
MLA 崔荣丽,et al."Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents".NANO RESEARCH 8.4(2015):1259-1268.
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