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Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents
Cui RL(崔荣丽); Li J(李娟); Huang H(黄换); Zhang MY(张铭倚); Guo XH(郭喜红); Li M(李敏); Dong JQ(董金泉); Sun BY(孙宝云); Xing GM(邢更妹); Cui, RL; Li, J; Huang, H; Zhang, MY; Guo, XH; Chang, YA; Li, M; Dong, JQ; Sun, BY; Xing, GM
2015
发表期刊NANO RESEARCH
卷号8期号:4页码:1259-1268
通讯作者孙宝云 ; 邢更妹
摘要Novel carbon nanohybrids based on unmodified metallofullerenes have been successfully fabricated for use as a new magnetic resonance imaging (MRI) contrast agent. The nanohybrids showed higher R (1) relaxivity and better brightening effect than Gd@C-82(OH) (X) , in T (1)-weighted MR images in vivo. This is a result of the proton relaxivity from the original gadofullerenes, which retained a perfect carbon cage structure and so might completely avoid the release of Gd3+ ions. A "secondary spin-electron transfer" relaxation mechanism was proposed to explain how the encaged Gd3+ ions of carbon nanohybrids interact with the surrounding water molecules. This approach opens new opportunities for developing highly efficient and low toxicity MRI contrast agents.
文章类型Article
关键词graphene oxide metallofullerene magnetic resonance imaging (MRI) nanohybrids
学科领域Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1007/s12274-014-0613-x
收录类别SCI ; CA
WOS类目Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
WOS记录号WOS:000353807500020
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被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/228294
专题多学科研究中心
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GB/T 7714
Cui RL,Li J,Huang H,et al. Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents[J]. NANO RESEARCH,2015,8(4):1259-1268.
APA 崔荣丽.,李娟.,黄换.,张铭倚.,郭喜红.,...&Xing, GM.(2015).Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents.NANO RESEARCH,8(4),1259-1268.
MLA 崔荣丽,et al."Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents".NANO RESEARCH 8.4(2015):1259-1268.
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