IHEP OpenIR  > 多学科研究中心
Protein crystallography from the perspective of technology developments
Su, XD; Zhang, H; Terwilliger, TC; Liljas, A; Xiao, JY; Dong, YH; Dong YH(董宇辉)
2015
发表期刊CRYSTALLOGRAPHY REVIEWS
卷号21期号:1-2页码:122-153
摘要Early on, crystallography was a domain of mineralogy and mathematics and dealt mostly with symmetry properties and imaginary crystal lattices. This changed when Wilhelm Conrad Rontgen discovered X-rays in 1895, and in 1912, Max von Laue and his associates discovered that X-ray irradiated salt crystals would produce diffraction patterns that could reveal the internal atomic periodicity of the crystals. In the same year, the father-and-son team, Henry and Lawrence Bragg successfully solved the first crystal structure of sodium chloride and the era of modern crystallography began. Protein crystallography (PX) started some 20 years later with the pioneering work of British crystallographers. In the past 50-60 years, the achievements of modern crystallography and particularly those in PX have been due to breakthroughs in theoretical and technical advancements such as phasing and direct methods; to more powerful X-ray sources such as synchrotron radiation; to more sensitive and efficient X-ray detectors; to ever faster computers and to improvements in software. The exponential development of PX has been accelerated by the invention and applications of recombinant DNA technology that can yield nearly any protein of interest in large amounts and with relative ease. Novel methods, informatics platforms and technologies for automation and high-throughput have allowed the development of large-scale, high-efficiency macromolecular crystallography efforts in the field of structural genomics. Very recently, the X-ray free-electron laser sources and its applications in PX have shown great potential for revolutionizing the whole field again in the near future.
文章类型Review
关键词computer programs and graphics structural genomics (SG) synchrotron radiation (SR) protein crystallization recombinant DNA techniques X-ray free-electron laser (XFEL) X-ray crystallography
学科领域Crystallography
DOI10.1080/0889311X.2014.973868
收录类别SCI ; EI
WOS类目Crystallography
WOS记录号WOS:000348313400005
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/228164
专题多学科研究中心
推荐引用方式
GB/T 7714
Su, XD,Zhang, H,Terwilliger, TC,et al. Protein crystallography from the perspective of technology developments[J]. CRYSTALLOGRAPHY REVIEWS,2015,21(1-2):122-153.
APA Su, XD.,Zhang, H.,Terwilliger, TC.,Liljas, A.,Xiao, JY.,...&董宇辉.(2015).Protein crystallography from the perspective of technology developments.CRYSTALLOGRAPHY REVIEWS,21(1-2),122-153.
MLA Su, XD,et al."Protein crystallography from the perspective of technology developments".CRYSTALLOGRAPHY REVIEWS 21.1-2(2015):122-153.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
96.pdf(830KB)期刊论文作者接受稿限制开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Su, XD]的文章
[Zhang, H]的文章
[Terwilliger, TC]的文章
百度学术
百度学术中相似的文章
[Su, XD]的文章
[Zhang, H]的文章
[Terwilliger, TC]的文章
必应学术
必应学术中相似的文章
[Su, XD]的文章
[Zhang, H]的文章
[Terwilliger, TC]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。