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Label-Free Au Cluster Used for in Vivo 2D and 3D Computed Tomography of Murine Kidneys
Wang YL(王亚玲); Xu C(徐超); Zhai J(翟焦); Gao FP(高福平); Liu R(刘茹); Gao J(高靓); Zhao YL(赵宇亮); Chai ZF(柴之芳); Gao XY(高学云); Wang, YL; Xu, C; Zhai, J; Gao, FP; Liu, R; Gao, L; Zhao, YL; Chai, ZF; Gao, XY
2015
发表期刊ANALYTICAL CHEMISTRY
卷号87期号:SI1页码:343-345
通讯作者高学云
文章类型Article
摘要Kidney disease is a worldwide health hazard. Noninvasive imaging modalities such as computed tomography are often used for diagnosis, to guide treatment, and to assess a disease state over the long-term. The physiology of the kidneys can be assessed with contrast agents. We present an albumin-stabilized Au cluster with red fluorescence and robust X-ray attenuation. In vivo studies revealed distribution of the Au clusters in the liver, spleen, and kidneys, with excretion mostly via the kidneys. Under optimal conditions, this agent can outline the anatomy of mouse kidneys on 2D and 3D computed tomography imaging, with clear visualization of the renal collecting system and ureters. This is a promising agent for kidney visualization and disease diagnosis.
学科领域Chemistry
DOI10.1021/ac503887c
收录类别SCI ; EI ; CA
WOS类目Chemistry, Analytical
WOS记录号WOS:000347590400024
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/228156
专题院士
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多学科研究中心
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Wang YL,Xu C,Zhai J,et al. Label-Free Au Cluster Used for in Vivo 2D and 3D Computed Tomography of Murine Kidneys[J]. ANALYTICAL CHEMISTRY,2015,87(SI1):343-345.
APA 王亚玲.,徐超.,翟焦.,高福平.,刘茹.,...&Gao, XY.(2015).Label-Free Au Cluster Used for in Vivo 2D and 3D Computed Tomography of Murine Kidneys.ANALYTICAL CHEMISTRY,87(SI1),343-345.
MLA 王亚玲,et al."Label-Free Au Cluster Used for in Vivo 2D and 3D Computed Tomography of Murine Kidneys".ANALYTICAL CHEMISTRY 87.SI1(2015):343-345.
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