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High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging
Wu, Z; Gao, K; Chen, J; Wang, DJ; Wang, SH; Chen, H; Bao, Y; Shao, QG; Wang, ZL; Zhang, K; Zhu, PP; Wu, Z; Zhang K(张凯); Zhu PP(朱佩平); Wu ZY(吴自玉)
2015
Source PublicationMEDICAL PHYSICS
ISSN0094-2405
Volume42Issue:2Pages:741-749
SubtypeArticle
AbstractPurpose: Grating-based x-ray phase contrast imaging is considered as one of the most promising techniques for future medical imaging. Many different methods have been developed to retrieve phase signal, among which the phase stepping (PS) method is widely used. However, further practical implementations are hindered, due to its complex scanning mode and high radiation dose. In contrast, the reverse projection (RP) method is a novel fast and low dose extraction approach. In this contribution, the authors present a quantitative analysis of the noise properties of the refraction signals retrieved by the two methods and compare their sensitivities. Methods: Using the error propagation formula, the authors analyze theoretically the signal-to-noise ratios (SNRs) of the refraction images retrieved by the two methods. Then, the sensitivities of the two extraction methods are compared under an identical exposure dose. Numerical experiments are performed to validate the theoretical results and provide some quantitative insight. Results: The SNRs of the two methods are both dependent on the system parameters, but in different ways. Comparison between their sensitivities reveals that for the refraction signal, the RP method possesses a higher sensitivity, especially in the case of high visibility and/or at the edge of the object. Conclusions: Compared with the PS method, the RP method has a superior sensitivity and provides refraction images with a higher SNR. Therefore, one can obtain highly sensitive refraction images in grating-based phase contrast imaging. This is very important for future preclinical and clinical implementations. (C) 2015 American Association of Physicists in Medicine.
Keywordgrating-based phase contrast imaging information extraction methods signal-to-noise ratio sensitivity
Subject AreaRadiology, Nuclear Medicine & Medical Imaging
DOI10.1118/1.4905490
Indexed BySCI ; ADS
Language英语
WOS Research AreaRadiology, Nuclear Medicine & Medical Imaging
WOS SubjectRadiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000349229600023
ADS Bibcode2015MedPh..42..741W
ADS URLhttps://ui.adsabs.harvard.edu/abs/2015MedPh..42..741W
ADS CITATIONShttps://ui.adsabs.harvard.edu/abs/2015MedPh..42..741W/citations
Citation statistics
Cited Times:7 [ADS]
Document Type期刊论文
Identifierhttp://ir.ihep.ac.cn/handle/311005/228125
Collection多学科研究中心
Recommended Citation
GB/T 7714
Wu, Z,Gao, K,Chen, J,et al. High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging[J]. MEDICAL PHYSICS,2015,42(2):741-749.
APA Wu, Z.,Gao, K.,Chen, J.,Wang, DJ.,Wang, SH.,...&吴自玉.(2015).High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging.MEDICAL PHYSICS,42(2),741-749.
MLA Wu, Z,et al."High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging".MEDICAL PHYSICS 42.2(2015):741-749.
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