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Distribution of ytterbium-169 in rat brain after intravenous injection
Xiao HQ(肖海清); Li FL(李福亮); Zhang ZY(张智勇); Feng LX(冯流星); Li ZJ(李子杰); Yang JH(杨巨华); Chai ZF(柴之芳); Xiao, HQ; Li, FL; Zhang, ZY; Feng, LX; Li, ZJ; Yang, JH; Chai, ZF
2005
Source PublicationTOXICOLOGY LETTERS
Volume155Issue:2Pages:#REF!
Corresponding AuthorChai, ZF (reprint author), Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, POB 918, Beijing 100039, Peoples R China.
SubtypeArticle
AbstractIt is well known that lanthanides have come into extensive and rapid use in a number of fields. As a result, more and more lanthanides are getting into the environment and food chains. However, the distributions of lanthanides in brain are not yet very clear. In this study, adult Sprague-Dawley male rats were intravenously injected with 0.5 ml of (YbCl3)-Yb-169 solution (containing 10 mug Yb). The brains were perfused with saline to minimize the blood influence. The radioactivities of Yb-169 in the five brain regions (hypothalamus, cerebellum, hippocampus, corpus striatum and cerebral cortex) were counted. The results suggested that Yb did enter into the brain. Though only about 0.005% of the given dose was accumulated in the brain, Yb seemed to remain in the brain for long time. The highest specific activities were observed in the hypothalamus, hippocampus and cerebellum. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
Keywordytterbium brain lanthanides distribution radioactive tracer technique
Subject AreaToxicology
DOI10.1016/j.toxlet.2004.09.021
Indexed BySCI
WOS SubjectToxicology
WOS IDWOS:000226484400005
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Document Type期刊论文
Identifierhttp://ir.ihep.ac.cn/handle/311005/227182
Collection院士
多学科研究中心
Recommended Citation
GB/T 7714
Xiao HQ,Li FL,Zhang ZY,et al. Distribution of ytterbium-169 in rat brain after intravenous injection[J]. TOXICOLOGY LETTERS,2005,155(2):#REF!.
APA 肖海清.,李福亮.,张智勇.,冯流星.,李子杰.,...&Chai, ZF.(2005).Distribution of ytterbium-169 in rat brain after intravenous injection.TOXICOLOGY LETTERS,155(2),#REF!.
MLA 肖海清,et al."Distribution of ytterbium-169 in rat brain after intravenous injection".TOXICOLOGY LETTERS 155.2(2005):#REF!.
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