IHEP OpenIR  > 多学科研究中心
Effects of lanthanum on composition, crystal size, and lattice structure of femur bone mineral of Wistar rats
Huang, J; Zhang, TL; Xu, SJ; Li, RC; Wang, K; Zhang, J; Xie, YN; Zhang J(张静); Xie YN(谢亚宁)
2006
发表期刊CALCIFIED TISSUE INTERNATIONAL
卷号78期号:4页码:#REF!
通讯作者Zhang, TL (reprint author), Capital Univ Med Sci, Sch Pharmaceut Sci, 10 Xitoutiao, Beijing 100054, Peoples R China.
摘要The application of lanthanum (La) in industry, medicine, and agriculture may cause accumulation of the element in human body. This article examines the effects of La on the femur bone mineral of male Wistar rats after administration of La(NO3)(3) by gavage at the dose of 2.0 mg La(NO3)(3) center dot kg(-1) center dot day(-1) over a 6-month period. Chemical analysis confirmed La accumulation in bone and loss in bone mineral. Thermogravimetric analysis showed a decrease in the mineral-to-matrix ratio and an increase in carbonate content. Fourier-transform infrared spectrometry revealed elevation in the contents of labile carbonate and acidic phosphate. The synchrotron radiation small-angle X-ray scattering study presented a smaller mean thickness of the mineral crystals in the bone of La-treated rats. The synchrotron radiation-extended X-ray absorption fine structure analysis indicated that the La treatment resulted in a lowered disorder in the crystals. The smaller size, more adsorbed labile carbonate, and more acidic phosphate made the bone mineral easier to dissolve, as revealed in the kinetic measurement of bone demineralization. These findings suggest that La retards bone maturation of rats.
文章类型Article
关键词lanthanum bone mineral crystal size lattice structure rat
学科领域Endocrinology & Metabolism
DOI10.1007/s00223-005-0294-2
收录类别SCI
WOS类目Endocrinology & Metabolism
WOS记录号WOS:000236751000007
引用统计
被引频次:22[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/227147
专题多学科研究中心
推荐引用方式
GB/T 7714
Huang, J,Zhang, TL,Xu, SJ,et al. Effects of lanthanum on composition, crystal size, and lattice structure of femur bone mineral of Wistar rats[J]. CALCIFIED TISSUE INTERNATIONAL,2006,78(4):#REF!.
APA Huang, J.,Zhang, TL.,Xu, SJ.,Li, RC.,Wang, K.,...&谢亚宁.(2006).Effects of lanthanum on composition, crystal size, and lattice structure of femur bone mineral of Wistar rats.CALCIFIED TISSUE INTERNATIONAL,78(4),#REF!.
MLA Huang, J,et al."Effects of lanthanum on composition, crystal size, and lattice structure of femur bone mineral of Wistar rats".CALCIFIED TISSUE INTERNATIONAL 78.4(2006):#REF!.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2527.pdf(174KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Huang, J]的文章
[Zhang, TL]的文章
[Xu, SJ]的文章
百度学术
百度学术中相似的文章
[Huang, J]的文章
[Zhang, TL]的文章
[Xu, SJ]的文章
必应学术
必应学术中相似的文章
[Huang, J]的文章
[Zhang, TL]的文章
[Xu, SJ]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 2527.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。