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Preliminary study on application of artificial neural network to the diagnosis of Alzheimer's disease with magnetic resonance imaging
Deng XY(邓小元); Deng, XY; Li, KC; Liu, SL
1999
发表期刊CHINESE MEDICAL JOURNAL
卷号112期号:3页码:#REF!
通讯作者Deng, XY (reprint author), Inst High Energy Phys, POB 918-14, Beijing 100039, Peoples R China.
文章类型Article
摘要Objective Artificial neural network is first used in the measurement study of brain of Alzheimer's disease using MRI, and a completely new pattern discriminating method is adopted, so as to take advantage of MRI to diagnose and identify AD patients. Methods 12 patients with probable AD (aged 65.33 +/- 8.62 years) and 36 normal controls matched with age and gender (aged 65.81 +/- 7.37 years) were studied. MRI are performed on Siemens Magnetorn IMPACT 1.0 T; eight interesting brain structures including sixteen regions (left and right) indices are measured and studied; SPSS software and BP network software made by authors respectively were used to process and analyze the measured data. Results Using artificial neural network to the same regions and data, both the sensitivity and accuracy were found higher than using the traditional discrimination function analysis method; the indices of amygdala, hippocampus, parahippocampal gyrus, temporal lobe, and temporal horn, these five structures could completely differentiate AD from normal controls; new cases were successfully diagnosed. Conclusions Artificial neural network combining with MRI is probable to become a useful and reliable clinical tool to diagnose AD patients.
关键词artificial neural network Alzheimer's disease magnetic resonance imaging
学科领域General & Internal Medicine
收录类别SCI
WOS类目Medicine, General & Internal
WOS记录号WOS:000079139900010
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/227095
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GB/T 7714
Deng XY,Deng, XY,Li, KC,et al. Preliminary study on application of artificial neural network to the diagnosis of Alzheimer's disease with magnetic resonance imaging[J]. CHINESE MEDICAL JOURNAL,1999,112(3):#REF!.
APA 邓小元,Deng, XY,Li, KC,&Liu, SL.(1999).Preliminary study on application of artificial neural network to the diagnosis of Alzheimer's disease with magnetic resonance imaging.CHINESE MEDICAL JOURNAL,112(3),#REF!.
MLA 邓小元,et al."Preliminary study on application of artificial neural network to the diagnosis of Alzheimer's disease with magnetic resonance imaging".CHINESE MEDICAL JOURNAL 112.3(1999):#REF!.
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