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Visual search in Alzheimer's disease - fMRI study
Hao, J; Li, KC; Li, K; Zhang, DX; Wang, W; Yan, B; Yang, YH; Wang, Y; Chen, Q; Shan, BC; Zhou, XL; Li K(李可); Yan B(闫镔); Dan BC(单保慈)
2004
发表期刊MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS
卷号3150页码:#REF!
通讯作者Hao, J (reprint author), Capital Univ Med Sci, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China.
文章类型Article; Proceedings Paper
摘要The aim was to investigate the neural basis of visual attention deficits in Alzheimer's disease (AD) patients using functional MRI. Thirteen AD patients and 13 age-matched controls participated in the experiment of two visual search tasks, one was a pop-out task, the other was a conjunction task. The fMRI data were collected on a 1-5T MRI system and analyzed by SPM99. Both groups revealed almost the same networks engaged in both tasks, including the superior parietal lobule (SPL), frontal and occipito-temporal cortical regions (OTC), primary visual cortex and some subcortical structures. AD patients have a particular impairment in the conjunction task. The most pronounced differences were more activity in the SPL in controls and more activity in the OTC in AD patients. These results imply that the mechanisms controlling spatial shifts of attention axe impaired in AD patients.
学科领域Computer Science; Radiology, Nuclear Medicine & Medical Imaging
收录类别SCI
WOS类目Computer Science, Interdisciplinary Applications ; Computer Science, Theory & Methods ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000223567700025
引用统计
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/226923
专题多学科研究中心
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GB/T 7714
Hao, J,Li, KC,Li, K,et al. Visual search in Alzheimer's disease - fMRI study[J]. MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS,2004,3150:#REF!.
APA Hao, J.,Li, KC.,Li, K.,Zhang, DX.,Wang, W.,...&单保慈.(2004).Visual search in Alzheimer's disease - fMRI study.MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS,3150,#REF!.
MLA Hao, J,et al."Visual search in Alzheimer's disease - fMRI study".MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS 3150(2004):#REF!.
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