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Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials
Zhang ZY(张智勇); Zhao YL(赵宇亮); Chai ZF(柴之芳); Zhang, ZY; Zhao, YL; Chai, ZF
刊名CHINESE SCIENCE BULLETIN
2009
卷号54期号:2页码:#REF!
关键词radiotracer nanoparticles toxicology pharmacology quantitative analysis biodistribution
学科分类Science & Technology - Other Topics
DOI10.1007/s11434-009-0016-7
通讯作者Chai, ZF (reprint author), Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Techn, Beijing 100049, Peoples R China.
文章类型Article
英文摘要With the rapid development of nanosciences and nanotechnology, a wide variety of manufactured nanomaterials are now used in commodities, pharmaceutics, cosmetics, biomedical products, and industries. While nanomaterials possess more novel and unique physicochemical properties than bulk materials, they also have an unpredictable impact on human health. In the pharmacology and toxicology studies of nanomaterials, it is essential to know the basic behavior in vivo, i.e. absorption, distribution, metabolism, and excretion (ADME) of these newly designed materials. Radiotracer techniques are especially well suited to such studies and have got the chance to demonstrate their enchantment. In this paper, radiolabeling methods for carbon nanomaterials, metallic and metal oxide nanoparticles, etc. are summarized and the applications of the radiolabeled nanomaterials in pharmacology and toxicology studies are outlined.
类目[WOS]Multidisciplinary Sciences
收录类别SCI
WOS记录号WOS:000263128500001
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/226677
专题院士_期刊论文
推荐引用方式
GB/T 7714
Zhang ZY,Zhao YL,Chai ZF,et al. Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials[J]. CHINESE SCIENCE BULLETIN,2009,54(2):#REF!.
APA 张智勇,赵宇亮,柴之芳,Zhang, ZY,Zhao, YL,&Chai, ZF.(2009).Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials.CHINESE SCIENCE BULLETIN,54(2),#REF!.
MLA 张智勇,et al."Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials".CHINESE SCIENCE BULLETIN 54.2(2009):#REF!.
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