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Tissue contents and intracellular distribution of selenium and iodine in human tissues studied by neutron activation analysis
Chen CY(陈春英); Zhao JJ(赵九江); Gao YX(高愈希); Chai ZF(柴之芳); Chen, CY; Zhao, JJ; Gao, YX; Chai, ZF
2005
发表期刊CHEMIA ANALITYCZNA
卷号50期号:1页码:#REF!
通讯作者Chen, CY (reprint author), Chinese Acad Sci, Lab Nucl Analyt Tech, POB 918, Beijing 100039, Peoples R China.
文章类型Article
摘要Selenium and iodine are two essential elements in living systems. In this paper, the tissue contents and subcellular distributions of selenium and iodine in human liver, kidney and heart samples were studied by neutron activation analysis (NAA). Certified reference materials were used as analytical quality control. Selenium was highly enriched in human kidney, followed by liver and then heart. In contrast, iodine was only enriched in liver. Different subcellular distribution patterns were also found in different tissues. In addition, selenium was mainly enriched in mitochondria and nuclei, whereas the lowest concentration of iodine was in the soluble fractions of cells. About 45-70% of total Se and I were in the nuclear fractions. The present data can reflect the long-term accumulation of selenium and iodine in human body. Our study also provides the reference data of selenium and iodine in human important tissues and the corresponding subcellular fractions.
关键词human tissues selenium iodine intracellular distribution neutron activation analysis
学科领域Chemistry
收录类别SCI
WOS类目Chemistry, Analytical
WOS记录号WOS:000228014300013
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被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/226650
专题院士
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GB/T 7714
Chen CY,Zhao JJ,Gao YX,et al. Tissue contents and intracellular distribution of selenium and iodine in human tissues studied by neutron activation analysis[J]. CHEMIA ANALITYCZNA,2005,50(1):#REF!.
APA 陈春英.,赵九江.,高愈希.,柴之芳.,Chen, CY.,...&Chai, ZF.(2005).Tissue contents and intracellular distribution of selenium and iodine in human tissues studied by neutron activation analysis.CHEMIA ANALITYCZNA,50(1),#REF!.
MLA 陈春英,et al."Tissue contents and intracellular distribution of selenium and iodine in human tissues studied by neutron activation analysis".CHEMIA ANALITYCZNA 50.1(2005):#REF!.
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