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Investigation of selenium distribution in subcellular fractions of human liver by neutron activation analysis
Chen CY(陈春英); Zhang PQ(章佩群); Hou XL(侯小琳); Chai ZF(柴之芳); Chen, CY; Zhang, PQ; Hou, XL; Chai, ZF
1999
发表期刊BIOLOGICAL TRACE ELEMENT RESEARCH
卷号25965页码:#REF!
通讯作者Chen, CY (reprint author), Chinese Acad Sci, Inst High Energy Phys, POB 2732, Beijing 100080, Peoples R China.
文章类型Article; Proceedings Paper
摘要Selenium is an important and essential trace element to living systems. In the article, two methods of instrumental neutron activation analysis and hydride generation-atomic fluorescence spectrometry were applied to determine Se in biological samples and the accuracy was evaluated by several reference materials. The subcellular distribution of selenium in human liver samples, which were obtained from normal subjects who had an accidental death, was investigated by differential centrifugation combined with INAA. Selenium was mainly enriched in mitochondria, nuclei, and cytosol. Almost half of the total Se content existed in nuclei as a result of the large amount in liver and the high Se concentration. Generally, the highest Se concentration in the mitochondrial fractions of each liver sample suggested that Se had important functions in this Liver component.
关键词selenium subcellular distribution human liver neutron activation analysis
学科领域Biochemistry & Molecular Biology; Endocrinology & Metabolism
DOI10.1007/BF02784199
收录类别SCI
WOS类目Biochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS记录号WOS:000084610100016
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/226389
专题院士
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GB/T 7714
Chen CY,Zhang PQ,Hou XL,et al. Investigation of selenium distribution in subcellular fractions of human liver by neutron activation analysis[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,1999,25965:#REF!.
APA 陈春英.,章佩群.,侯小琳.,柴之芳.,Chen, CY.,...&Chai, ZF.(1999).Investigation of selenium distribution in subcellular fractions of human liver by neutron activation analysis.BIOLOGICAL TRACE ELEMENT RESEARCH,25965,#REF!.
MLA 陈春英,et al."Investigation of selenium distribution in subcellular fractions of human liver by neutron activation analysis".BIOLOGICAL TRACE ELEMENT RESEARCH 25965(1999):#REF!.
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