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Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy
Yu, AH; Li, KC; Li L(李琳); Dan BC(单保慈); Li, L; Shan, BC; Wang, YP; Xue, SF
2008
发表期刊EUROPEAN JOURNAL OF RADIOLOGY
卷号65期号:1页码:#REF!
通讯作者Li, KC (reprint author), Capital Univ Med Sci, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China.
文章类型Article
摘要Purpose: The purpose of this study was to analyze whole-brain white matter changes in medial temporal lobe epilepsy (MTLE). Materials and methods: We studied 23 patients with MTLE and 13 age- and sex-matched healthy control subjects using voxel-based morphometry (VBM) on T1-weighted 3D datasets. The seizure focus was right sided in I I patients and left sided in 12. The data were collected on a 1.5 T MR system and analyzed by SPM 99 to generate white matter density maps. Results: Voxel-based morphometry revealed diffusively reduced white matter in MTLE prominently including bilateral frontal lobes, bilateral temporal lobes and corpus callosum. White matter reduction was also found in the bilateral cerebellar hemispheres in the left MTLE group. Conclusion: VBM is a simple and automated approach that is able to identify diffuse whole-brain white matter reduction in MTLE. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
关键词epilepsy white matter magnetic resonance imaging voxel-based morphometry
学科领域Radiology, Nuclear Medicine & Medical Imaging
DOI10.1016/j.ejrad.2007.04.011
收录类别SCI
WOS类目Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000253086400011
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/226039
专题多学科研究中心
中国科学院高能物理研究所_中国散裂中子源
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GB/T 7714
Yu, AH,Li, KC,Li L,et al. Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy[J]. EUROPEAN JOURNAL OF RADIOLOGY,2008,65(1):#REF!.
APA Yu, AH.,Li, KC.,李琳.,单保慈.,Li, L.,...&Xue, SF.(2008).Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy.EUROPEAN JOURNAL OF RADIOLOGY,65(1),#REF!.
MLA Yu, AH,et al."Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy".EUROPEAN JOURNAL OF RADIOLOGY 65.1(2008):#REF!.
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