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3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN
Yu MJ(于梅娟); Yang FF(杨飞飞); Chu WS(储旺盛); Zhao HF(赵海峰); Gao B(高斌); Wu ZY(吴自玉); Yu, MJ; Yang, FF; Chu, WS; Wang, Y; Zhao, HF; Gao, B; Zhao, W; Sun, JP; Wu, FM; Zhang, XW; Shi, YY; Wu, ZY
2008
发表期刊BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
卷号374期号:1页码:#REF!
通讯作者Chu, WS (reprint author), Chinese Acad Sci, Inst High Energy Phys, Beijing Synchrotron Radiat Facil, 19B YuquanLu, Beijing 100049, Peoples R China.
摘要Zinc is an important component of many proteins that play key roles in transcription, translation, and catalysis. Kti11p, DESR1, both belonging to a protein family characterized by a CSL zinc finger domain, and the co-catalytic zinc-protein PML containing a Zn(2+) binding domain called RING or C(3)HC(4) finger are all structurally determined by NMR although the zinc sites are silent to this spectroscopical method. The comparison of X-ray absorption near-edge spectroscopy (XANES) data for the three proteins demonstrates that fingerprints effect is a reliable method for a primary characterization of ligand species. Ab initio full MS Calculations performed by MAN are applied to obtain chemical and stereo structural information around the Zn ion in Kti11p. For the first time this high-spatial resolution technique confirms the formation of a stable Zn tetrahedral configuration with four sulfur ligands, and returns extremely accurate bond angle information between ligands. (C) 2008 Elsevier Inc. All rights reserved.
文章类型Article
关键词zinc motif Kti11p EXAFS XANES fingerprints MXAN
学科领域Biochemistry & Molecular Biology; Biophysics
DOI10.1016/j.bbrc.2008.06.116
收录类别SCI
WOS类目Biochemistry & Molecular Biology ; Biophysics
WOS记录号WOS:000258798700006
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/225596
专题多学科研究中心
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GB/T 7714
Yu MJ,Yang FF,Chu WS,et al. 3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2008,374(1):#REF!.
APA 于梅娟.,杨飞飞.,储旺盛.,赵海峰.,高斌.,...&Wu, ZY.(2008).3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,374(1),#REF!.
MLA 于梅娟,et al."3D local structure around Zn in Kti11p as a representative Zn-(Cys)4 motif as obtained by MXAN".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 374.1(2008):#REF!.
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