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Cytotoxic Potential of Silver Nanoparticles
Zhang TL(张田露); Wang LM(王黎明); Zhang, TL; Wang, LM; Chen, Q; Chen, CY; Chen CY(陈春英)
2014
发表期刊YONSEI MEDICAL JOURNAL
卷号55期号:2页码:283-291
摘要Silver nanoparticles (AgNPs) have been widely used in industrial, household, and healthcare-related products due to their excellent antimicrobial activity With increased exposure of AgNPs to human beings, the risk of safety has attracted much attention from the public and scientists. In review of recent studies, we discuss the potential impact of AgNPs on individuals at the cell level. In detail, we highlight the main effects mediated by AgNPs on the cell, such as cell uptake and intracellular distribution, cytotoxicity, genotoxicity, and immunological responses, as well as some of the major factors that influence these effects in vitro and in vivo, such as dose, time, size, shape, surface chemistry, and cell type. At the end, we summarize the main influences on the cell and indicate the challenges in this field, which may be helpful for assessing the risk of AgNPs in future.
关键词Silver nanoparticles cell effects cytotoxicity genotoxicity immunological response risk assessment
学科领域General & Internal Medicine
DOI10.3349/ymj.2014.55.2.283
收录类别SCI
WOS记录号WOS:000331916800001
引用统计
被引频次:99[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/225387
专题多学科研究中心
推荐引用方式
GB/T 7714
Zhang TL,Wang LM,Zhang, TL,et al. Cytotoxic Potential of Silver Nanoparticles[J]. YONSEI MEDICAL JOURNAL,2014,55(2):283-291.
APA 张田露.,王黎明.,Zhang, TL.,Wang, LM.,Chen, Q.,...&陈春英.(2014).Cytotoxic Potential of Silver Nanoparticles.YONSEI MEDICAL JOURNAL,55(2),283-291.
MLA 张田露,et al."Cytotoxic Potential of Silver Nanoparticles".YONSEI MEDICAL JOURNAL 55.2(2014):283-291.
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