IHEP OpenIR  > 多学科研究中心
Structural and functional analysis show that the Escherichia coli uncharacterized protein YjcS is likely an alkylsulfatase
Liang, YJ; Gao ZQ(高增强); Dong YH(董宇辉); 刘全胜;Gao, ZQ; Dong, YH; Liu, QS
2014
发表期刊PROTEIN SCIENCE
卷号23期号:10页码:1442-1450
摘要Sodium dodecyl sulfate (SDS) is a widely used anionic surfactant in industry and research settings, and is known to have a detrimental effect to the environment. The pathway of SDS degradation by bacteria is initiated by an alkylsulfatase and the oxidized product, 1-dodecanoic acid, subsequently enters into the beta-oxidation pathway and is used as a carbon source. In this work, we solved the crystal structure of Escherichia coli uncharacterized protein YjcS and identified that it belongs to the Type III alkylsulfatase with a signal peptide (residues 1-29) at the N terminus. YjcS hydrolyzed SDS and the double mutant D184N-H185A located in the conserved HXHXDH catalytic motif abolished this activity.
关键词alkylsulfatase hydrolase metalloenzyme X-ray crystallography metallo-beta-lactamase
学科领域Biochemistry & Molecular Biology
DOI10.1002/pro.2528
收录类别SCI
WOS记录号WOS:000342210600012
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/225317
专题多学科研究中心
推荐引用方式
GB/T 7714
Liang, YJ,Gao ZQ,Dong YH,et al. Structural and functional analysis show that the Escherichia coli uncharacterized protein YjcS is likely an alkylsulfatase[J]. PROTEIN SCIENCE,2014,23(10):1442-1450.
APA Liang, YJ,高增强,董宇辉,刘全胜;Gao, ZQ,Dong, YH,&Liu, QS.(2014).Structural and functional analysis show that the Escherichia coli uncharacterized protein YjcS is likely an alkylsulfatase.PROTEIN SCIENCE,23(10),1442-1450.
MLA Liang, YJ,et al."Structural and functional analysis show that the Escherichia coli uncharacterized protein YjcS is likely an alkylsulfatase".PROTEIN SCIENCE 23.10(2014):1442-1450.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
11469.pdf(1100KB)期刊论文作者接受稿限制开放CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liang, YJ]的文章
[高增强]的文章
[董宇辉]的文章
百度学术
百度学术中相似的文章
[Liang, YJ]的文章
[高增强]的文章
[董宇辉]的文章
必应学术
必应学术中相似的文章
[Liang, YJ]的文章
[高增强]的文章
[董宇辉]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。