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Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing
Wang JY(汪景怡); 刘茹;Wang, JY; Liu, R; Su, YM; Li, W
2014
发表期刊JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷号14期号:6页码:4058-4065
摘要In this report, embedded single-wall carbon nanotubes (SWCNTs) nanoparticles in plasma membrane inducing cellular calcium outflow imbalancing are disclosed. Compared ssDNA-SWCNTs with polystyrene (PS) nanoparticles, we analyzed the cytotoxicity of these nanoparticles and the effect of these nanoparticles on intracellular Ca2+ ion levels by depletion of Ca2+ from the endoplasmic reticulum (ER) evoked by Thapsigargin (Tg) in SKN-SH cells. The results had shown that ssDNA-SWCNTs and PS nanoparticles have no cytotoxicity on SKN-SH cells. However, contrary to PS nanoparticles, cellular Ca2+ ion outflow imbalancing was investigated in SKN-SH cells after pretreated with ssDNA-SWCNTs induced by Tg, which could be proposed mainly due to the interaction of embedded ssDNA-SWCNTs with cellular membrane.
关键词Carbon Nanotubes Nanoparticles Cellular Membrane Calcium
学科领域Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1166/jnn.2014.8229
收录类别SCI
WOS记录号WOS:000332339500008
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/225125
专题多学科研究中心
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GB/T 7714
Wang JY,刘茹;Wang, JY,Liu, R,et al. Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2014,14(6):4058-4065.
APA 汪景怡,刘茹;Wang, JY,Liu, R,Su, YM,&Li, W.(2014).Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,14(6),4058-4065.
MLA 汪景怡,et al."Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 14.6(2014):4058-4065.
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