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Toxicological Properties of Nanomaterials
Zhang MY(张铭倚); Jin JJ(金俊江); Chang YN(常亚南); Chang XL(常雪灵); 邢更妹;Zhang, MY; Jin, JJ; Chang, YN; Chang, XL; Xing, GM
2014
发表期刊JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷号14期号:1页码:717-729
摘要The development of engineered nanomaterials opens tremendous opportunities for their application as therapeutic and diagnostic tools, as well as in the fields of consumer products. As the newly developed material subtype, they exhibit great activities for the high ratio of surface to total atoms. In the bio-system, the activity can render nanomaterials some negative outcomes for their unexpected deposition in organs and cells, the cellular response to the exogenous substance and the interfacial reaction with biomolecules. In this review, we have discussed the evolution of nanotoxicology studies in the past ten years mainly emerging from our laboratory The early in vivo studies mainly focused on the biokinetic of inhaled nanoparticles and their impacts on mammal tissues, such as the central nervous system, respiratory system, cardiovascular system and so on. Then the scope extended to engineered nanomaterials used as food additives and medicines, as well as their influence on alimentary and reproductive systems. In vitro experiments to study the nanoparticle-cell interaction and nanoparticle-biomolecule interplay are indispensable to reveal the mechanisms behind the macroscopic phenomenon. In addition, novel tools such as new model organisms and synchrotron radiation-based techniques are used to facilitate our understanding of the toxicology profile of nanomaterials.
关键词Nanomaterials Toxicological Property In Vivo In Vitro Bioactivity
学科领域Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1166/jnn.2014.9198
收录类别SCI
WOS记录号WOS:000331803900044
引用统计
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/225120
专题多学科研究中心
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GB/T 7714
Zhang MY,Jin JJ,Chang YN,et al. Toxicological Properties of Nanomaterials[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2014,14(1):717-729.
APA 张铭倚.,金俊江.,常亚南.,常雪灵.,邢更妹;Zhang, MY.,...&Xing, GM.(2014).Toxicological Properties of Nanomaterials.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,14(1),717-729.
MLA 张铭倚,et al."Toxicological Properties of Nanomaterials".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 14.1(2014):717-729.
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