Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor
刘蕾(多); Yang C(杨春); Zhao K(赵凯); Liu, L; Yang, C; Zhao, K; Li, JY; Wu, HC;; Li JY(李敬源); Wu HC(吴海臣)
刊名NATURE COMMUNICATIONS
2013
卷号4页码:2989
学科分类Science & Technology - Other Topics
DOI10.1038/ncomms3989
英文摘要An important issue in nanopore sensing is to construct stable and versatile sensors that can discriminate analytes with minute differences. Here we report a means of creating nanopores that comprise ultrashort single-walled carbon nanotubes inserted into a lipid bilayer. We investigate the ion transport and DNA translocation through single-walled carbon nanotube nanopores and find that our results are fundamentally different from previous studies using much longer single-walled carbon nanotubes. Furthermore, we utilize the new single-walled carbon nanotube nanopores to selectively detect modified 5-hydroxymethylcytosine in single-stranded DNA, which may have implications in screening specific genomic DNA sequences. This new nanopore platform can be integrated with many unique properties of carbon nanotubes and might be useful in molecular sensing such as DNA-damage detection, nanopore DNA sequencing and other nanopore-based applications.
收录类别SCI
WOS记录号WOS:000329398200001
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被引频次:67[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224468
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_多学科研究中心
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Liu L,Yang C,Zhao K,et al. Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor[J]. NATURE COMMUNICATIONS,2013,4:2989.
APA 刘蕾.,杨春.,赵凯.,Liu, L.,Yang, C.,...&吴海臣.(2013).Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor.NATURE COMMUNICATIONS,4,2989.
MLA 刘蕾,et al."Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor".NATURE COMMUNICATIONS 4(2013):2989.
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