IHEP OpenIR  > 院士  > 期刊论文
Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology
Chen, CY; Li YF(李玉锋); Li, YF; Qu, Y; Chai, ZF; Zhao, YL; Chai ZF(柴之芳); Zhao YL(赵宇亮)
刊名CHEMICAL SOCIETY REVIEWS
2013
卷号42期号:21页码:8266-8303
学科分类Chemistry
DOI10.1039/c3cs60111k
英文摘要Manufactured nanomaterials with novel physicochemical properties are an important basis for nanosciences and related technologies. Nanotoxicology, aiming to understand the principles of interactions at the nano-bio interface and the relationship between the physicochemical properties of nanomaterials and their toxicological profiles, has become a new frontier in nanoscience. Nearly one decade of nanotoxicology research has shown that the interactions between nanomaterials and proteins, cells, animals, humans and the environment as well as the underlying mechanisms of toxicity for nanomaterials are remarkably complicated, requiring dedicated analytical methodology and tools. Because of their advantages of absolute quantification, high sensitivity, excellent accuracy and precision, low matrix effects and non-destructiveness, nuclear analytical techniques have been playing important roles in the study of nanotoxicology. A systematic summary and comprehensive review of the advanced nuclear analytical and related techniques in nanotoxicology is greatly needed. In this review article, we present a comprehensive overview of nuclear analytical techniques applied to the physicochemical characterization of nanomaterials, structural analysis of bio-nano interactions, visualization of nanomaterials in vitro, quantification of bio-distribution, bio-accumulation, and transformation of nanomaterials in vivo. As important complementary tools, optical imaging technologies are also highlighted. Future directions regarding advanced nuclear analytical approaches for nanotoxicology are also discussed. The rapid development of advanced light source-based techniques will enable new high-throughput screening techniques and provide high sensitivity with low detection limits, which are required for the distribution, imaging, and structural analysis of nanomaterials, and the molecular information of biomarkers for all aspects of nanotoxicology.
收录类别SCI
WOS记录号WOS:000325489600005
引用统计
被引频次:38[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224307
专题院士_期刊论文
中国科学院高能物理研究所_多学科研究中心
推荐引用方式
GB/T 7714
Chen, CY,Li YF,Li, YF,et al. Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology[J]. CHEMICAL SOCIETY REVIEWS,2013,42(21):8266-8303.
APA Chen, CY.,李玉锋.,Li, YF.,Qu, Y.,Chai, ZF.,...&赵宇亮.(2013).Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology.CHEMICAL SOCIETY REVIEWS,42(21),8266-8303.
MLA Chen, CY,et al."Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology".CHEMICAL SOCIETY REVIEWS 42.21(2013):8266-8303.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
7692.pdf(10445KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, CY]的文章
[李玉锋]的文章
[Li, YF]的文章
百度学术
百度学术中相似的文章
[Chen, CY]的文章
[李玉锋]的文章
[Li, YF]的文章
必应学术
必应学术中相似的文章
[Chen, CY]的文章
[李玉锋]的文章
[Li, YF]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 7692.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。