Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals
Qiu, XZ; Wang YL(王亚玲); Cui YY(崔艳艳); Wang, YL; Cui, YY; Sun, ZP; Liu, R; Huang, WH; Zhao, F; Zu, Y; Yuan, H; Chang, XL; Gao, XY;; Sun ZP(孙志鹏); Liu R(刘茹); Zhao F(赵峰); Zu Y(祖艳); Yuan H(袁慧); Chang XL(常雪灵); Gao XY(高学云)
刊名JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
2012
卷号12期号:9页码:6893-6899
关键词Gold Nanorods Multi-Signal Cell-Penetrating Peptide Raman Fluorescent MGITC Dark-Field
学科分类Chemistry; Science & Technology - Other Topics; Materials Science; Physics
DOI10.1166/jnn.2012.6458
英文摘要Surface functionalized gold nanorods (GNRs) with three optical signals and the ability to track and observe live cells was investigated. The Cetyltrimethyl Ammonium Bromide (CTAB) was used as the shape-directing agent to develop GNRs with uniform size and aspect ratio. The as-synthesized GNRs can strongly enhance the Raman signal of the attached MGITC on the GNRs. Polyethylene glycol (SH-PEG-COOH) and SH-PEG-FITC were attached with GNRs through ligand exchange with CTAB. They can stabilize the GNRs, reduce the cytotoxicity and provide fluorescence signal. A cell-penetrating peptide was covalently conjugated with SH-PEG-COOH to assist the GNRs to enter living cell. After cultured with the MCF-7 cells, the surfaced functionalized Au nanorods can enter the MCF-7 cells and be tracking with enhanced MGITC Raman signal, FITC fluorescence, and Rayleigh scatter signal.
收录类别SCI
WOS记录号WOS:000308856200004
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被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224284
专题中国科学院高能物理研究所_多学科研究中心_期刊论文
中国科学院高能物理研究所_多学科研究中心
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Qiu, XZ,Wang YL,Cui YY,et al. Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2012,12(9):6893-6899.
APA Qiu, XZ.,王亚玲.,崔艳艳.,Wang, YL.,Cui, YY.,...&高学云.(2012).Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,12(9),6893-6899.
MLA Qiu, XZ,et al."Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 12.9(2012):6893-6899.
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