IHEP OpenIR  > 院士
Nano-CeO2 Exhibits Adverse Effects at Environmental Relevant Concentrations
Zhang HF(张海峰); He X(何潇); Zhang ZY(张智勇); Zhang, HF; He, XA; Zhang, ZY; Zhang, P; Li, YY; Ma, YH; Kuang, YS; Zhao, YL; Chai, ZF;; 张鹏(多); Li YY(李媛媛); Ma YH(马宇辉); Yashu Kuang; Zhao YL(赵宇亮); Chai ZF(柴之芳)
2011
Source PublicationENVIRONMENTAL SCIENCE & TECHNOLOGY
Volume45Issue:8Pages:3725-3730
AbstractCeria nanoparticles (nano-CeO2), due to their widespread applications, have attracted a lot of concern about their toxic effects on both human health and the environment. The present work aimed to evaluate the in vivo effects of nano-CeO2 (8.5 nm) on Caenorhabditis elegans (C. elegans) at environmental relevant concentrations (molar concentrations ranging from 1 nM to 100 nM). The results indicate that nano-CeO2 could induce ROS accumulation and oxidative damage in C. elegans, and finally lead to a decreased lifespan. The most surprising thing is that the mean lifespan of nematodes was significantly decreased by 12% even at the exposure level of 1 nM (p < 0.01). In vitro tests suggest that the ability of nano-CeO2 to catalyze ROS generation was involved in the mechanism for its toxicity to C. elegans. To our best knowledge, this is the first case in which nanoparticles exhibit adverse effects on organisms at such low concentrations (1 nM-100 nM). So, our findings indicate the importance of nanotoxicological investigations at: environmentally relevant concentrations and will attract more attentions on the risks of NPs exposure.
Subject AreaEngineering; Environmental Sciences & Ecology
DOI10.1021/es103309n
Indexed BySCI ; ADS
WOS IDWOS:000289341300075
ADS Bibcode2011EnST...45.3725Z
ADS URLhttps://ui.adsabs.harvard.edu/abs/2011EnST...45.3725Z
ADS CITATIONShttps://ui.adsabs.harvard.edu/abs/2011EnST...45.3725Z/citations
Citation statistics
Cited Times:43 [ADS]
Document Type期刊论文
Identifierhttp://ir.ihep.ac.cn/handle/311005/224241
Collection院士
多学科研究中心
Recommended Citation
GB/T 7714
Zhang HF,He X,Zhang ZY,et al. Nano-CeO2 Exhibits Adverse Effects at Environmental Relevant Concentrations[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2011,45(8):3725-3730.
APA 张海峰.,何潇.,张智勇.,Zhang, HF.,He, XA.,...&柴之芳.(2011).Nano-CeO2 Exhibits Adverse Effects at Environmental Relevant Concentrations.ENVIRONMENTAL SCIENCE & TECHNOLOGY,45(8),3725-3730.
MLA 张海峰,et al."Nano-CeO2 Exhibits Adverse Effects at Environmental Relevant Concentrations".ENVIRONMENTAL SCIENCE & TECHNOLOGY 45.8(2011):3725-3730.
Files in This Item:
File Name/Size DocType Version Access License
7363.pdf(2007KB)期刊论文作者接受稿限制开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[张海峰]'s Articles
[何潇]'s Articles
[张智勇]'s Articles
Baidu academic
Similar articles in Baidu academic
[张海峰]'s Articles
[何潇]'s Articles
[张智勇]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[张海峰]'s Articles
[何潇]'s Articles
[张智勇]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.