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Structural and SAXS analysis of the budding yeast SHU-complex proteins
She Z(佘准); Gao ZQ(高增强); Liu Y(刘颖); She, Z; Gao, ZQ; Liu, Y; Wang, WJ; Liu, GF; Shtykova, EV; Xu, JH; Dong, YH; Wang WJ(王文佳); Liu GF(刘广峰); Xu JH(徐建华); Dong YH(董宇辉)
2012
发表期刊FEBS LETTERS
卷号586期号:16页码:2306-2312
摘要In Saccharomyces cerevisiae, four proteins, Shu1, Shu2, Psy3 and Csm2, form a stable SHU-complex both in vivo and in vitro. These proteins are involved in the early stages of the homologous recombination DNA damage repair process. In this paper, the crystal structure of the Psy3-Csm2 sub-complex is presented at 1.8 angstrom resolution and successfully fitted into our small angle X-ray scattering (SAXS) data of the SHU-complex. Taken together with our electrophoretic mobility shift assay (EMSA) results, a model is proposed for the SHU-protein complex coupled with DNA.
关键词DNA repair Protein-complex Paralog SAXS DNA binding
学科领域Biochemistry & Molecular Biology; Biophysics; Cell Biology
DOI10.1016/j.febslet.2012.06.024
收录类别SCI
WOS记录号WOS:000306694800016
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224199
专题多学科研究中心
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GB/T 7714
She Z,Gao ZQ,Liu Y,et al. Structural and SAXS analysis of the budding yeast SHU-complex proteins[J]. FEBS LETTERS,2012,586(16):2306-2312.
APA 佘准.,高增强.,刘颖.,She, Z.,Gao, ZQ.,...&董宇辉.(2012).Structural and SAXS analysis of the budding yeast SHU-complex proteins.FEBS LETTERS,586(16),2306-2312.
MLA 佘准,et al."Structural and SAXS analysis of the budding yeast SHU-complex proteins".FEBS LETTERS 586.16(2012):2306-2312.
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