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An Electrochemical Immunosensor for Fullerenol Detection Based on the Generated Antibody
Yang SY(杨尚元); Cui RL(崔荣丽); Yang, SY; Guo, XH; Cui, RL; Dong, JQ; Xing, GM; Liu, XX; Yuan, H; Tao, Y; Zhang, ZY; Sun, BY;; Dong JQ(董金泉); Xing GM(邢更妹); Liu XX(刘潇潇); Yuan H(袁慧); Tao Y(陶冶); Zhang ZY(张智勇); Sun BY(孙宝云); Guo XH(郭喜红)
2013
发表期刊ANALYTICAL LETTERS
卷号46期号:14页码:2213-2222
摘要As the nanomaterial fullerenol has attracted much attention in various fields, there is a need to develop convenient and effective detection methods for its determination. In this paper, the polyclonal antibody against fullerenol was obtained by immunization of rabbits with the fullerenol protein conjugate. Based on this new antibody against fullerenol, an electrochemical immunosensor was constructed by employing the redox couple to sense the generated antibody and fullerenol interaction. The peak current decreased after the interaction of fullerenol with the immunosensor. Using this strategy, the concentration of fullerenol in the range of 1x10(-5) to 1mgmL(-1) was detected with a good linear relationship, and the lowest detection limit was about 3x10(-6)mgmL(-1). This immunosensor was used to detect and quantify fullerenol.
关键词Electrochemical immunosensor Fullerenol Polyclonal antibody
学科领域Chemistry
DOI10.1080/00032719.2013.798795
收录类别SCI
WOS记录号WOS:000323997100007
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被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224195
专题多学科研究中心
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GB/T 7714
Yang SY,Cui RL,Yang, SY,et al. An Electrochemical Immunosensor for Fullerenol Detection Based on the Generated Antibody[J]. ANALYTICAL LETTERS,2013,46(14):2213-2222.
APA Yang SY.,Cui RL.,Yang, SY.,Guo, XH.,Cui, RL.,...&Guo XH.(2013).An Electrochemical Immunosensor for Fullerenol Detection Based on the Generated Antibody.ANALYTICAL LETTERS,46(14),2213-2222.
MLA Yang SY,et al."An Electrochemical Immunosensor for Fullerenol Detection Based on the Generated Antibody".ANALYTICAL LETTERS 46.14(2013):2213-2222.
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