F-18-FDG PET Study Reveals Brain Functional Changes During Attention in Rats
Xi, W; Su, DT; Nie BB(聂彬彬); Dan BC(单保慈); Nie, BB; Yu, YQ; Shan, BC; Chen, QZ; Tian, M; Zhang, H
刊名JOURNAL OF NUCLEAR MEDICINE
2013
卷号54期号:11页码:1969-1973
关键词positron emission tomography (PET) 18F-FDG neurology attention rat model
学科分类Radiology, Nuclear Medicine & Medical Imaging
DOI10.2967/jnumed.113.123000
英文摘要Attentional impairments are seen in many clinical syndromes, including attention deficit hyperactivity disorder, schizophrenia, and Alzheimer disease. Understanding the mechanism of attention can be helpful for the diagnosis and treatment of these diseases. The aim of this study was to assess brain glucose metabolic changes in a rat model of attention. Methods: Small-animal PET studies were performed at 4 stages. Statistical parametric mapping was used for image analysis. Results: Increased F-18-FDG uptake was found in the lateral hypothalamic area and left accumbens nucleus in the learning condition. Under the attentive condition, increased F-18-FDG uptake was observed in the right retrosplenial cortex but F-18-FDG uptake was decreased in the right medial geniculate nucleus. F-18-FDG uptake change in the right retrosplenial cortex was negatively correlated with correct latency of behavior performance. Conclusion: F-18-FDG small-animal PET imaging provided novel findings on attention-related glucose metabolic changes, which were significantly correlated with the behavior performance in this rat model.
收录类别SCI
WOS记录号WOS:000326876800023
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224182
专题中国科学院高能物理研究所_核技术应用研究中心_期刊论文
中国科学院高能物理研究所_核技术应用研究中心
推荐引用方式
GB/T 7714
Xi, W,Su, DT,Nie BB,et al. F-18-FDG PET Study Reveals Brain Functional Changes During Attention in Rats[J]. JOURNAL OF NUCLEAR MEDICINE,2013,54(11):1969-1973.
APA Xi, W.,Su, DT.,聂彬彬.,单保慈.,Nie, BB.,...&Zhang, H.(2013).F-18-FDG PET Study Reveals Brain Functional Changes During Attention in Rats.JOURNAL OF NUCLEAR MEDICINE,54(11),1969-1973.
MLA Xi, W,et al."F-18-FDG PET Study Reveals Brain Functional Changes During Attention in Rats".JOURNAL OF NUCLEAR MEDICINE 54.11(2013):1969-1973.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
6900.pdf(874KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Xi, W]的文章
[Su, DT]的文章
[聂彬彬]的文章
百度学术
百度学术中相似的文章
[Xi, W]的文章
[Su, DT]的文章
[聂彬彬]的文章
必应学术
必应学术中相似的文章
[Xi, W]的文章
[Su, DT]的文章
[聂彬彬]的文章
相关权益政策
暂无数据
收藏/分享
文件名: 6900.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。