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High-speed X-ray microscopy by use of high-resolution zone plates and synchrotron radiation
Hou, QY; Wang, ZL; Gao, K; Pan, ZY; Wang, DJ; Ge, X; Zhang, K; Hong, YL; Zhu, PP; Wu, ZY; Zhang K(张凯); Hong YL(洪友丽); Zhu PP(朱佩平); Wu ZY(吴自玉)
2012
发表期刊ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷号404期号:5页码:1327-1330
摘要X-ray microscopy based on synchrotron radiation has become a fundamental tool in biology and life sciences to visualize the morphology of a specimen. These studies have particular requirements in terms of radiation damage and the image exposure time, which directly determines the total acquisition speed. To monitor and improve these key parameters, we present a novel X-ray microscopy method using a high-resolution zone plate as the objective and the matching condenser. Numerical simulations based on the scalar wave field theory validate the feasibility of the method and also indicate the performance of X-ray microscopy is optimized most with sub-10-nm-resolution zone plates. The proposed method is compatible with conventional X-ray microscopy techniques, such as computed tomography, and will find wide applications in time-resolved and/or dose-sensitive studies such as living cell imaging.
关键词X-ray microscopy High-resolution zone plate Radiation dose Exposure time Synchrotron radiation
学科领域Biochemistry & Molecular Biology; Chemistry
DOI10.1007/s00216-012-6218-x
收录类别SCI
WOS记录号WOS:000307957800008
引用统计
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224128
专题多学科研究中心
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GB/T 7714
Hou, QY,Wang, ZL,Gao, K,et al. High-speed X-ray microscopy by use of high-resolution zone plates and synchrotron radiation[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2012,404(5):1327-1330.
APA Hou, QY.,Wang, ZL.,Gao, K.,Pan, ZY.,Wang, DJ.,...&吴自玉.(2012).High-speed X-ray microscopy by use of high-resolution zone plates and synchrotron radiation.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,404(5),1327-1330.
MLA Hou, QY,et al."High-speed X-ray microscopy by use of high-resolution zone plates and synchrotron radiation".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 404.5(2012):1327-1330.
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