Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography
Liu, F; Zhang,刘双全; 单保慈; Y; Liu, SQ; Zhang, B; Liu, Q; Yang, Y; Zhang, B; Luo, JW; Shan, BC; Bai, J
刊名IEEE TRANSACTIONS ON MULTIMEDIA
2013
卷号15期号:5页码:1025-1030
关键词Dual-modality imaging fluorescence photodynamic therapy photothermal therapy [F-18]FDG-PET
学科分类Computer Science; Telecommunications
DOI10.1109/TMM.2013.2244204
英文摘要Fluorescence imaging can track the expression of fluorescent protein and F-18-fluorodeoxyglucose based positron emission tomography ([F-18]FDG-PET) can evaluate the changes of [F-18]FDG uptake in tumor cells during the antitumor treatment. In this work, fluorescence imaging and [F-18]FDG-PET were both employed to monitor tumor response to Au nanorod-indocyanine green (AuNR-ICG) conjugates mediated therapy in a subcutaneous MDA-MB-231 mouse xenograft model. Serial fluorescence and [F-18]FDG-PET images following the antitumor treatment were obtained and quantitative analysis revealed significant decreases in fluorescence intensity and metabolic activity in tumors treated with AuNR-ICG conjugates under near infrared laser irradiation. The results suggest that the combination of fluorescence and [F-18]FDG-PET imaging can provide a noninvasive tool to assess the tumor response to antitumor therapy on a molecular scale.
收录类别SCI
WOS记录号WOS:000324763600006
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被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/224097
专题中国科学院高能物理研究所_核技术应用研究中心_期刊论文
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Liu, F,Zhang,刘双全,单保慈; Y,et al. Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography[J]. IEEE TRANSACTIONS ON MULTIMEDIA,2013,15(5):1025-1030.
APA Liu, F.,Zhang,刘双全.,单保慈; Y.,Liu, SQ.,Zhang, B.,...&Bai, J.(2013).Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography.IEEE TRANSACTIONS ON MULTIMEDIA,15(5),1025-1030.
MLA Liu, F,et al."Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography".IEEE TRANSACTIONS ON MULTIMEDIA 15.5(2013):1025-1030.
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