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Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor
He, ZZ; Xue, X; 肖剑;Xiao, J; Liu, J
2013
发表期刊COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
卷号112期号:3页码:356-366
摘要This paper is aimed at investigating the capacity of using combined cryosurgical and hyperthermic modality for treating knee bone tumor with complex shape. An anatomical model for human knee was constructed and a three-dimensional (3D) finite element analysis was developed to determine temperature distribution of the tissues subject to single freezing (SF), single heating (SH) and alternate freezing-heating (AFH), respectively. The heat fluxes of the probes wall and the ablation volume are particularly tracked to comparatively evaluate the ablation ability of different probe configurations with varied diameter, number and active working length. As example, an effective conformal treatment strategy via one time's insertion while cyclic freezing-heating using multiple probes is designed for a predefined knee bone tumor ablation. Both SF and SH could create large enough ablation volume, while it is hard for them to perform a conformal treatment on irregular and slender knee tumor. As an alternative, AFH could form a flexible and controlled shape and volume of the ablation by changing the size and number of the probes and adjusting their insertion depth. In addition, a thermal protection method is considered to reduce cryoinjury of the health tissue. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
关键词Cryosurgery Hyperthermia Alternate freezing-heating Knee bone tumor Anatomical CAD model
学科领域Computer Science; Engineering; Medical Informatics
DOI10.1016/j.cmpb.2013.07.023
收录类别SCI
WOS记录号WOS:000325750100005
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/223950
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He, ZZ,Xue, X,肖剑;Xiao, J,et al. Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor[J]. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,2013,112(3):356-366.
APA He, ZZ,Xue, X,肖剑;Xiao, J,&Liu, J.(2013).Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor.COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE,112(3),356-366.
MLA He, ZZ,et al."Anatomical model-based finite element analysis of the combined cryosurgical and hyperthermic ablation for knee bone tumor".COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 112.3(2013):356-366.
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