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Biological characterizations of [Gd@C-82(OH)(22)](n) nanoparticles as fullerene derivatives for cancer therapy
Meng, J; Liang, XJ; Chen, XY; Zhao, YL; Zhao YL(赵宇亮)
2013
发表期刊INTEGRATIVE BIOLOGY
卷号5期号:1页码:43-47
摘要Malignant tumor disease is one of the leading causes of human death in many countries. Currently, chemotherapy is considered highly efficient for cancer treatment. However, the clinical application of conventional chemotherapeutic agents is limited because of their high toxicity. With the development of nanotechnology, engineered nanomaterials have been widely and increasingly used in biomedical fields such as biomedicine. Thus, the use of engineered nanomaterials has become a promising approach to cancer treatment. Many newly fabricated nanomaterials with unique characteristics exhibit favorable therapeutic and diagnostic properties, implying their enormous potential as biomedical candidates. [Gd@C-82(OH)(22)](n) is a new type of metallofullerenol nanoparticle with high anti-tumor activity but low toxicity. In this article, the properties and biological effects of [Gd@C-82(OH)(22)](n) are summarized, and their possible mechanisms are analyzed.
学科领域Cell Biology
DOI10.1039/c2ib20145c
收录类别SCI
WOS记录号WOS:000312391300005
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被引频次:38[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/223784
专题多学科研究中心
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GB/T 7714
Meng, J,Liang, XJ,Chen, XY,et al. Biological characterizations of [Gd@C-82(OH)(22)](n) nanoparticles as fullerene derivatives for cancer therapy[J]. INTEGRATIVE BIOLOGY,2013,5(1):43-47.
APA Meng, J,Liang, XJ,Chen, XY,Zhao, YL,&赵宇亮.(2013).Biological characterizations of [Gd@C-82(OH)(22)](n) nanoparticles as fullerene derivatives for cancer therapy.INTEGRATIVE BIOLOGY,5(1),43-47.
MLA Meng, J,et al."Biological characterizations of [Gd@C-82(OH)(22)](n) nanoparticles as fullerene derivatives for cancer therapy".INTEGRATIVE BIOLOGY 5.1(2013):43-47.
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