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Preliminary Study of Oxidative Stress in Human Hepatocellular Carcinoma and Adjacent Normal Liver Tissues
Yu HW(于红伟); Chen CY(陈春英); Wang JX(王江雪); Hongwei Yu; Chunying Chen; Jiangxue Wang; Yuxi Gao; Guilong Deng; Yingbin Liu; Shuyou Peng; Zhifang Chai; Chai ZF(柴之芳)
2006
发表期刊中国肿瘤临床
期号1页码:11--14
通讯作者于红伟
摘要OBJECTIVE The antioxidative system in human hepatocellular carcinoma was investigated.METHODS The activities of cytosolic catalase (CAT), superoxide dismutase, glutathione peroxidase (GSH-Px), glutathione S-tranferase and levels of reduced glutathione, total protein thiols and malondialdehyde were assayed in 10 cases of hepatocellular carcinoma and adjacent normal liver.RESULTS Hepatoma tissues showed higher activities of CAT, GSH-Px and lower content of total antioxidative capacity compared to adjacent normal liver tissue (P<0.05).CONCLUSION These findings suggest that the antioxidative defenserelated enzymes and antioxidants are largely regulated in hepatoma cells.However, the mechanism which is not clear requires further investigation.
文献类型期刊论文
条目标识符http://ir.ihep.ac.cn/handle/311005/223216
专题院士
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GB/T 7714
Yu HW,Chen CY,Wang JX,et al. Preliminary Study of Oxidative Stress in Human Hepatocellular Carcinoma and Adjacent Normal Liver Tissues[J]. 中国肿瘤临床,2006(1):11--14.
APA 于红伟.,陈春英.,王江雪.,Hongwei Yu.,Chunying Chen.,...&柴之芳.(2006).Preliminary Study of Oxidative Stress in Human Hepatocellular Carcinoma and Adjacent Normal Liver Tissues.中国肿瘤临床(1),11--14.
MLA 于红伟,et al."Preliminary Study of Oxidative Stress in Human Hepatocellular Carcinoma and Adjacent Normal Liver Tissues".中国肿瘤临床 .1(2006):11--14.
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